Protein Alignment CG3225 and DHX30

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Alignment Length: 685
• Identity: 208/685 - (30%)
• Similarity: 320/685 - (46%)
• Gaps: 100/685 - (14%)

  Fly    42 EQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGL-----IGITEPR 101
            ::..:||:..:||.||..:|:|.||::.|:||.||:|::||.|.| .:.|:|.     :.||:||
Human   500 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLE-RYVTEGRGARCNVIITQPR 563

  Fly   102 RVSTVTLANRVAQERGELVGDTVGYVVRFLESM--SSCTKIKFMTEGILLREVLADPLLTQYGVI 164
            |:|.|::|.||:.|.|..:...||:.|| |||.  |....:.|.|.|||||::.::|.|.....:
Human   564 RISAVSVAQRVSHELGPSLRRNVGFQVR-LESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHV 627

  Fly   165 IVDEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRM 229
            ||||.|||::.||.:|.|||.:.|...:|:|::.|||.|...||.:|     |...| :.:.|.|
Human   628 IVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYF-----GGCPV-IKVPGFM 686

  Fly   230 HPVSNFYL---------------------NEPCADYVKETVETVWKLHQKEPPGDILAFLTGQEE 273
            :||...||                     .:.||..:....:.|..:..:..||.||.||.|.:|
Human   687 YPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQE 751

  Fly   274 VLEALDLLREYIASSEQENLKVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIV 338
            :......|:|.:...|.:.| :||::.::...||.::|..||.|.||:|||||||||||||..||
Human   752 IKGVQQRLQEALGMHESKYL-ILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIV 815

  Fly   339 YVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYEALAPRQPP 403
            :|:|.|..|.:.|:.||....|..|.||:|:.|||.|||||.:.|..|.|:.:|..|.:.|.|.|
Human   816 HVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVP 880

  Fly   404 EMRRSELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYL--- 465
            |:.|:.|...:||.|         ...|.....:.|..|::|. .:.|:||...|.:.:|.|
Human   881 EILRTPLENLVLQAK---------IHMPEKTAVEFLSKAVDSP-NIKAVDEAVILLQEIGVLDQR 935

  Fly   466 ---------LAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRPASAVAQQSGRIAHR 521
                     ||.:.....|:|.:.::....|...::.:::.|.     ..|.|:..|....:...
Human   936 EYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-----RDPFSSSLQNRAEVDKV 995

  Fly   522 KFEVAE---GDFITMLNAYTGFVEEGMTKEFCGQYFLIYRNLKRAHSLREQLITVARKKYGIPIF 583
            |..::.   .|.:..:.|..|:.|....::...:...:..||..|.|||  .|....|::...|:
Human   996 KALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLR--FIHGLIKQFSENIY 1058

  Fly   584 ----------------SCK--GDVEKLCK-CITAGFFTQVAYLHHSGVYRQISSGTELAIHPNST 629
                            .|.  .:.|:|.| .:.||.:..:..:....|.||..      ..|||.
Human  1059 EAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGK------FKPNSV 1117

  Fly   630 LYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLT 664
            .|....      |.:|..........|.::..|||
Human  1118 TYRTKS------GNILLHKSTINREATRLRSRWLT 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	208/685 (30%)
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	180/552 (33%)
		OB_NTP_bind	1086..1173	CDD:400182	16/73 (22%)