Protein Alignment CG3225 and Dhx37

DIOPT Version :9

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_017176254.1
• Gene: Dhx37 / 208144
• MGIID: 3028576
• Length: 1161
• Species: Mus musculus
• Alignment Length: 807
• Identity: 264/807 - (32%)
• Similarity: 381/807 - (47%)
• Gaps: 203/807 - (25%)

  Fly    34 VNHNMGLMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTK-GLIGI 97
            ||....:.|:|.:|||......|:..:.:|.:||:.|||||||:|||||:|||.|:.:: .:||:
Mouse   235 VNRTPEMQEERLKLPILAEEQAIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDSIIGV 299

  Fly    98 TEPRRVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYG 162
            ||||||:.|.::.|||:|. .|....|.|.:|:..:::..|:|||||:|:||:|:..|.||.:|.
Mouse   300 TEPRRVAAVAMSQRVAKEM-NLSHRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYK 363

  Fly   163 VIIVDEAHERNMLTDMILGLLKKILRKRSS----LKLIISSATIDASFFSE---FFSWPGSGEVS 220
            |:|:||||||::.||::||||.:|:..|:.    |||:|.|||:....|::   .|:.|     .
Mouse   364 VVIIDEAHERSVYTDILLGLLSRIVALRAKRHLPLKLLIMSATLRVEDFTQNQRLFTTP-----P 423

  Fly   221 VKLSIEGRMHPVS-NFYLNEPCADYVKETVETVWKLHQKEPPGDILAFLTGQEEVLEALDLLRE- 283
            ..:.:|.|..||: :|....|..||..|....|.|:|:..|.|.||.|||||.||......||:
Mouse   424 PVIKVESRQFPVTVHFNKRTPLDDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKA 488

  Fly   284 --YIASSEQEN------------------------------------------------------ 292
              :..|..||.
Mouse   489 FPFRCSQPQEKEEDSAEGMRRFKKSRTRARKAQAMALPQINLDNYSVLPAGEGDEDREAEMDDEE 553

  Fly   293 ---------------------------LKVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAET 330
                                       |.|||:|..::...|..||..||:|||..|:|||:|||
Mouse   554 EALGSDLDLDLGDSEANEGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAET 618

  Fly   331 SITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYE 395
            |:|||||.||:|||.||.::|:..|...|..:..||:|||.||||||||..||..||||:.:.:.
Mouse   619 SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFG 683

  Fly   396 ALAPRQPPEMRRSELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDAID------- 453
            ......|||:.|..:...|||:|||.|..::.|.||:||..:.|::|.|.|.||.|:.
Mouse   684 DFEQFPPPEITRRPVEDLILQMKALSIEKVINFPFPTPPSVEALVAAEELLVALGALQAPPKQER 748

  Fly   454 ----EQGNLTKPV---GYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQSIF---SRPA 508
                :...|:.|:   |..::..|.:...:|||.:|.|.||....|.|:|.:.|:.:|   .|||
Mouse   749 MKKLQMSQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPYTIAIVAAMTVRELFEELDRPA 813

  Fly   509 SA---VAQQSGRIAHRKFEVAE--------------GDFITMLNAYTGFVEEGMTKEFCGQYFLI 556
            ::   :|:..||.|    .||:              ||.:.:|.|.......|.:.:||....|.
Mouse   814 ASEKELAELKGRRA----RVAQMKRTWAGQGPSLKLGDLMVLLGAVGACEYAGCSPQFCQANGLR 874

  Fly   557 YRNLKRAHSLREQLITVARKKYGIPIFSCKGDVEKLCKCITAGFF----------TQVAYLHHSG 611
            |:.:.....||.||.|...                 ..|..||.|          :||.||
Mouse   875 YKAMLEIRRLRGQLTTAVN-----------------AVCPEAGLFLDPKMQPPTESQVTYL---- 918

  Fly   612 VYRQISS---GTELA---------------------------IHPNSTLY-TLPQAQYVVYGELL 645
              |||.:   |..||                           |||:|.|: .||  ::|||.|::
Mouse   919 --RQIMAAGLGDHLARRVQSEDLLDPKWKNAYKTPLLDDPVFIHPSSVLFKELP--EFVVYQEIV 979

  Fly   646 QTTKLFMNYVTVIKREWLTELAPHYYQ 672
            :|||::|..|:.::.:|:..|.|.|.|
Mouse   980 ETTKMYMKGVSTVEIQWIPSLLPSYCQ 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	40..668	CDD:224557	259/795 (33%)
		DEXDc	64..202	CDD:238005	71/142 (50%)
		HELICc	289..380	CDD:197757	50/171 (29%)
		HA2	448..534	CDD:214852	30/119 (25%)
		OB_NTP_bind	<581..670	CDD:285018	33/129 (26%)
Dhx37	XP_017176254.1	HrpA	236..1009	CDD:224557	263/806 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820