Protein Alignment CG3225 and rha-1

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_495890.2
• Gene: rha-1 / 174417
• WormBaseID: WBGene00004355
• Length: 1301
• Species: Caenorhabditis elegans
• Alignment Length: 698
• Identity: 208/698 - (29%)
• Similarity: 327/698 - (46%)
• Gaps: 138/698 - (19%)

  Fly    43 QRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYE-WGWHTKGL---IGITEPRRV 103
            ||..||:.|||:.|:..:.:::|.::.||||.||||||.|:|.| :..::.|.   ..:::|||:
 Worm   377 QRGELPVAQYRENIVQTVAENRVTLIKGETGCGKSTQVAQFLLESFLENSNGASFNAVVSQPRRI 441

  Fly   104 STVTLANRVAQERGELVGDTVGYVVRFLESMSSCT-----KIKFMTEGILLREVLADPLLTQYGV 163
            |.::||.|||.||||.||:|.||.|||    .|.|     .|.|.|.|:|||  :.:..|.....
 Worm   442 SAISLAERVANERGEEVGETCGYNVRF----DSATPRPYGSIMFCTVGVLLR--MMENGLRGISH 500

  Fly   164 IIVDEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFF-SWPGSGEVSVKLSIEG 227
            :|:||.|||::.||.:|.:|::::.....|::::.|||||...|:.|| |.|..|...| :::.|
 Worm   501 VIIDEIHERDVDTDFVLIVLREMISTYRDLRVVLMSATIDTDLFTNFFSSIPDVGPTPV-ITMHG 564

  Fly   228 RMHPVSNFYLNE----------------------PCAD---------------------YVKETV 249
            |..||.:|||.:                      |..|                     .:.|::
 Worm   565 RTFPVQSFYLEDILHNLQHMPEEPDQKKRKKGGPPPPDDDEGDEEVDDKGRNMNILTDPSINESL 629

  Fly   250 ETVW-KLHQKEPP-----------------GDILAFLTGQEEVLEALDLLREYIASSEQENLKVL 296
            :|.. ::.:|:.|                 |.:|.||.|..|::...:.|.|:....:....::|
 Worm   630 KTAMSRISEKDIPFGVIEAILNDIASRGVDGAVLVFLPGWAEIMTLCNRLLEHQEFGQANKYEIL 694

  Fly   297 PMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLV 361
            |::..::|.:|..||...| |.||::::||||||||||..:|||||....|.:.|..........
 Worm   695 PLHSQLTSQEQRKVFNHYP-GKRKIIVSTNIAETSITIDDVVYVIDSCKAKERMYTSNNNMVHFA 758

  Fly   362 IVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYEALAPRQPPEMRRSELSGAILQLKALGIGNIL 426
            .|..||.:.|||.|||||:|.|..:.|.:|..:|||......||.|..|....|.:|.|.:|::.
 Worm   759 TVWASKTNVIQRRGRAGRVRAGYAFHLCSKMRFEALDDHGTAEMLRIPLHQIALTIKLLRLGSVG 823

  Fly   427 RF--DFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSE 489
            .|  ....|||...::.:...|.|:.|:|....||. :|.:||.:|...:::|:|.:...:|...
 Worm   824 EFLGKALQPPPYDMVVESEAVLQAMGALDRNLELTS-LGKMLARMPIEPVIAKVLILGTALGAGS 887

  Fly   490 EIITIIALLQVQSIFSRPASAVAQQ------SG---RIAHRKF--EVAEGDFITMLNAYTGFVEE 543
                  .:..|.|..|.|...|.::      ||   :.|..||  .||   .::::..|...|:.
 Worm   888 ------VMCDVASAMSFPTPFVPREKHHSRLSGTQRKFAGNKFSDHVA---IVSVIQGYREAVQM 943

  Fly   544 GMT---KEFCGQYFLIYRNLKRAHSLREQLITVARKKYGIP---IFSCKGDVEKLCKCITAGFFT 602
            |.:   :|||.:|.|....||.....|.|||.|.|.:...|   :|....:|
 Worm   944 GASAAEREFCERYSLSNPVLKMTDGARRQLIDVLRNQCSFPEDILFDISVNV------------- 995

  Fly   603 QVAYLHHSGVYRQIS---SGTELAIHPNSTLY-------TLPQAQYVV 640
                   :|..|:::   |...:|::||...|       |:.|:..::
 Worm   996 -------NGPDRELNLMRSLLVMALYPNVAYYVGKRKVLTIEQSSALI 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	208/698 (30%)
rha-1	NP_495890.2	DSRM_DHX9_rpt1	4..73	CDD:380683
		DSRM_DHX9_rpt2	169..244	CDD:380684
		DEAD-like_helicase_N	325..562	CDD:475120	77/191 (40%)
		HrpA	380..>897	CDD:441249	168/531 (32%)
		OB_NTP_bind	1005..1087	CDD:400182	7/32 (22%)