Protein Alignment CG3225 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 684
• Identity: 290/684 - (42%)
• Similarity: 422/684 - (61%)
• Gaps: 35/684 - (5%)

  Fly     1 MSTFKPKFLKPETDDAITDSAGGEQQSSAFVFNVNHNMGLMEQRERLPIRQYRDQILYCLEKHQV 65
            |:..|.|..|||..:|                 ....|.:.|.::.|||..:::.::..::.|.:
Mosquito   218 MAGTKKKDDKPELTEA-----------------QRKKMTIEETQKSLPIYPFKEDLIAAIQAHNI 265

  Fly    66 VILVGETGSGKSTQVPQYLYEWGWHTKG-LIGITEPRRVSTVTLANRVAQERGELVGDTVGYVVR 129
            :|:.|||||||:||:||||||.|:..:| .||.|:||||:.:::|.|||:|....:|:.|||.:|
Mosquito   266 LIIEGETGSGKTTQIPQYLYEAGFTNEGKKIGCTQPRRVAAMSVAARVAEEMAVKLGNEVGYSIR 330

  Fly   130 FLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIVDEAHERNMLTDMILGLLKKILRKRSSLK 194
            |.:..|..|.||:||:|.|.||.|::|.|..|.|:|:||||||.:.||::.||:|.|.|.|..||
Mosquito   331 FEDCTSERTVIKYMTDGTLHREFLSEPDLASYAVMIIDEAHERTLHTDILFGLVKDIARFRKDLK 395

  Fly   195 LIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRMHPVSNFYLNEPCADYVKETVETVWKLHQKE 259
            |:|||||:||..||:||      :.:....|.||.:||..||...|.|||:...|.:|.::|..:
Mosquito   396 LLISSATLDAEKFSDFF------DKAPIFRIPGRRYPVDIFYTKAPEADYIDACVVSVLQIHATQ 454

  Fly   260 PPGDILAFLTGQEEVLEALDLLREYI--ASSEQENLKVLPMYGSMSSTDQLSVFFTPPKGTRKVV 322
            |.||||.|||||||:....::|::.:  ..|:.:.|.:||:|.::.|..|..:|...|...|||:
Mosquito   455 PLGDILVFLTGQEEIEACQEMLQDRVKRLGSKLKELLILPIYANLPSDMQAKIFEPTPPNARKVI 519

  Fly   323 LATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYR 387
            |||||||||:||..|:||||.|:.|...:|.:|..::|::||:|||||.||||||||:.|||.:|
Mosquito   520 LATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMETLLVVPISKASANQRAGRAGRVAPGKCFR 584

  Fly   388 LYTKSDY-EALAPRQPPEMRRSELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDA 451
            |||...| ..|.....||::|..|..|:|.||.|||.::|.|||..|||.|.|:.|||.|:||.|
Mosquito   585 LYTAWAYNNELEDNTVPEIQRINLGNAVLMLKTLGIHDLLHFDFLDPPPHQTLILALEQLYALGA 649

  Fly   452 IDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQ-SIFSRPASAVAQQS 515
            ::..|.||| :|..:||.|...|::|||..|.:..|||||::|.|:|.|. :||.||...:....
Mosquito   650 LNHHGELTK-LGRRMAEFPVDPMMAKMLLASEKYKCSEEIVSIAAMLSVNGAIFYRPKDKIIHAD 713

  Fly   516 GRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEFCGQYFLIYRNLKRAHSLREQLITVARKKYGI 580
              .|.:.|....||.::::..|..:||...:.::|.:.|:.||::|||..:||||:.: .::..|
Mosquito   714 --TARKNFNHRHGDHLSLMQVYNQWVESDYSTQWCYENFIQYRSMKRARDVREQLVGL-MQRVEI 775

  Fly   581 PIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYRQISSGTELAIHPNSTLY-TLPQAQYVVYGEL 644
            .:.|.:.|...:.|.||||:|..||.|..||.|:.:....::.|||||.|: .||  ::::|.||
Mosquito   776 EMVSGESDTTNVRKAITAGYFYHVARLSKSGNYKTVKHNQDVMIHPNSALFEDLP--RWLLYHEL 838

  Fly   645 LQTTKLFMNYVTVIKREWLTELAPHYYQQTTVRD 678
            :.|||.||..|..|:.:||.|:|||||:...:.|
Mosquito   839 VFTTKEFMRSVIEIESKWLLEVAPHYYKPKELED 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	278/636 (44%)
l(2)37Cb	XP_319843.5	None