Protein Alignment CG3225 and Dhx57

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001157231.1
• Gene: Dhx57 / 106794
• MGIID: 2147067
• Length: 1388
• Species: Mus musculus
• Alignment Length: 788
• Identity: 228/788 - (28%)
• Similarity: 354/788 - (44%)
• Gaps: 192/788 - (24%)

  Fly    40 LMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGLIG-------- 96
            ::::|:.||..:.|:.||..|.|||||::.|.||.||:||:||::.:     ..|.|
Mouse   538 ILQERQLLPAWEERETILKLLSKHQVVVISGMTGCGKTTQIPQFILD-----NSLNGPPERVANI 597

  Fly    97 -ITEPRRVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQ 160
             .|:|||:|.:::|.|||:||.|.||.||||.:|.....||.|::.:.|.|:|||.:..|..|..
Mouse   598 ICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQG 662

  Fly   161 YGVIIVDEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFFSWPGSGEVSVKLSI 225
            ...|||||.|||...:|.:|.:||.|:.:|::|::|:.|||:||..||::||:      ...::|
Mouse   663 VTHIIVDEVHERTEESDFLLLVLKDIVMQRATLQVILMSATLDAGLFSKYFSY------CPVITI 721

  Fly   226 EGRMHPVSNFYLNEPCA------------------------------------------------ 242
            .||..||..|:|.:..|
Mouse   722 PGRAFPVDQFFLEDALAVTRYVLQDGSPYMRSMKQIAKEKLKARHNRTAQEEVEEDLRLSLHLQD 786

  Fly   243 -------------------------------------DYVKETVETV-----WKLHQKE--PPGD 263
                                                 |:.|..:|.:     |.:..|.  |||.
Mouse   787 EEESVKDTIPDQQLDFKQLLIRYKGVSKSVIKTMSVMDFEKVNLELIEALLEWIVDGKHAYPPGA 851

  Fly   264 ILAFLTGQEEVLEALDLLREYIASSEQENLK------VLPMYGSMSSTDQLSVFFTPPKGTRKVV 322
            :|.||.|..|:    .:|.|.:.|:...|.:      :.|::.|:||.:|.:||..||.|..|::
Mouse   852 VLVFLPGLAEI----KMLYEQLQSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPMGVTKII 912

  Fly   323 LATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYR 387
            ::||||||||||..:|||||.|.:|.|.|:.....:||....||:|:|:||.|||||:..|..:.
Mouse   913 ISTNIAETSITIDDVVYVIDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGRVASGVCFH 977

  Fly   388 LYTKSDY-EALAPRQPPEMRRSELSGAILQLKALGIGNI--LRFDFP---SPPPAQNLLSALESL 446
            |:|...| ..|..:|.||::|..|....|::|.|.:.:.  |:..|.   .||...:|.::...|
Mouse   978 LFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSTHNLQSVFSRLIEPPHIDSLRASKVRL 1042

  Fly   447 FALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRPASAV 511
            ..|.|:.....|| |:||.||.||....:.|::.:.....|.:..:||.|.|..:|.|..|....
Mouse  1043 RDLGALTPDEKLT-PLGYHLASLPVDVRIGKLMLLGSIFRCLDPALTIAASLAFKSPFVSPWDKK 1106

  Fly   512 AQQSGRIAHRK---FEVAEGDFITMLNAYTGFVEEGMTKE-------FCGQYFLIYRNLKRAHSL 566
            .:     |::|   |..|..|::.:|.||.|:  :..|||       :|.|.||..|.|:...||
Mouse  1107 EE-----ANQKKLEFAFANSDYLALLCAYKGW--QLSTKESARASYNYCRQNFLSGRTLQEMASL 1164

  Fly   567 REQLITV-----------------ARKKYGIPIFSCKGDV-------EKLCKCI-TAGFFTQVAY 606
            :.|...:                 .|.:.|..:....|:.       .||...: .|..:..|..
Mouse  1165 KRQFTELLSDIGFVKEGLRAKEIEKRAQGGDGVLDATGEEANTNAENPKLISAVLCAALYPNVVQ 1229

  Fly   607 LH---------HSGVYRQISSGTELA----------IHPNSTLYTLP--QAQYVVYGELLQTTKL 650
            :.         .|||.|......||.          |||:|..|.:.  .:.|::|.|.::|:::
Mouse  1230 VKTPEGKFQKTSSGVVRLQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRV 1294

  Fly   651 FMNYVTVI 658
            |:...:::
Mouse  1295 FIRDCSMV 1302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	228/788 (29%)
Dhx57	NP_001157231.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..154
		UBA_DHX57	181..218	CDD:270502
		RWD_DHX57	243..425	CDD:467661
		zf_CCCH_4	305..323	CDD:465719
		HrpA	545..>1172	CDD:441249	204/649 (31%)
		DEVH box	669..672		2/2 (100%)
		OB_NTP_bind	1215..1312	CDD:400182	18/88 (20%)