DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and Chl1

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_038964701.1	Gene:	Chl1 / 89828	RGDID:	620122	Length:	1224	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	105/452 - (23%)
Similarity:	173/452 - (38%)	Gaps:	108/452 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LSLSPAE----HSVVRYTNESLIVQCRS---PDPKVELHWKSPKGEIIREHKGRIHIEQTSTEQL 82
            |.|.||:    .|......::|:::|.:   |.|::|  |.....|:   .|||..|| ...:.|
  Rat   252 LLLPPAQIGSASSKTVLKGDTLLLECFAEGLPTPQIE--WSKLGSEL---PKGRATIE-IHEKTL 310

  Fly    83 KIVFAHIALADKGNWSCEAAD--GSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKGE 145
            ||  .:::..|:||:.|.|.:  |.. |..|.:||.:...:.:.........|....:|||.:||
  Rat   311 KI--ENVSYQDRGNYRCTANNLLGKA-SHDFHVIVEEPPRWKKKPQSAVYSTGSNGILLCEAEGE 372

  Fly   146 PQPNVTWHFNGQPISAGAADDSKFR---ILADGLLINKVTQNDTGEYACRAYQVNSIASDMQERT 207
            |||.:.|..||.||     ::..|.   :....:....:..|.|..|.|.|..::.        |
  Rat   373 PQPTIKWRVNGLPI-----ENHPFPGDVMFPREISFTNLQPNHTAVYQCEASNIHG--------T 424

  Fly   208 VLMKIEHKPIWSKTPFVSLK----YAYING-TATLMCEALAEPPANFTWYRKHNKLH--SNNRLY 265
            :|.. .:..:....|.:..|    |..:.| :|.|.||..|.|.|...| ...::.|  ...|.:
  Rat   425 ILAN-ANIDVVDVVPLIQTKNEENYETVVGYSAFLHCEYFASPKATVVW-EVADETHPLEGGRYH 487

  Fly   266 TIQSDSYWSSLTIHVLNTSAFD--NYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRGFNSNTF 328
            |.::.      |:.:..|:..|  :|.|...|.:|            |....||..:|  |:...
  Rat   488 THENG------TLEIERTTEEDAGSYSCWVDNTMG------------KAVITANLDIR--NATKL 532

  Fly   329 DVVLSAPRGPPDSPMGVNGFRIEYMTEM--EFKTDAG-------KWTNARRKD-YAFE------- 376
            .|....||.|.           .::.|:  |.:.|:.       .|:    || .|||
  Rat   533 RVFPKNPRIPK-----------SHVLELYCESQCDSHLKHSLKLSWS----KDGEAFEMNGTEDG 582

  Fly   377 ----EGATFLLTNL--EPDTVYLVRA--ASRNLAGFSDFTKV---EKYKTLSLEPRVSSGVK 427
                :||...::|:  |...:|...|  |..:.:|.:..|.:   :..:.|.|..|.:..|:
  Rat   583 RIVIDGANLTISNISGEDQGIYSCSAQTALDSTSGKTQVTVLGVPDPPRNLLLSERQNRSVR 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	24/86 (28%)
		I-set	128..202	CDD:254352	20/76 (26%)
		Ig	133..>193	CDD:299845	19/62 (31%)
		IG_like	228..307	CDD:214653	20/83 (24%)
		Ig	235..305	CDD:143165	18/73 (25%)
		FN3	312..415	CDD:238020	26/130 (20%)
Chl1	XP_038964701.1	Ig	34..125	CDD:416386
		Ig strand A	34..38	CDD:409353
		Ig strand A'	43..47	CDD:409353
		Ig strand B	52..59	CDD:409353
		Ig strand C	65..70	CDD:409353
		Ig strand C'	73..75	CDD:409353
		Ig strand D	81..84	CDD:409353
		Ig strand E	89..93	CDD:409353
		Ig strand F	104..112	CDD:409353
		Ig strand G	115..125	CDD:409353
		IgI_2_L1-CAM_like	134..224	CDD:409432
		Ig strand B	148..152	CDD:409432
		Ig strand C	162..166	CDD:409432
		Ig strand E	185..189	CDD:409432
		Ig strand F	200..205	CDD:409432
		Ig strand G	216..219	CDD:409432
		Ig	261..343	CDD:416386	25/90 (28%)
		Ig strand B	273..277	CDD:409353	1/3 (33%)
		Ig strand C	286..290	CDD:409353	1/5 (20%)
		Ig strand E	308..312	CDD:409353	1/3 (33%)
		Ig strand F	322..327	CDD:409353	2/4 (50%)
		Ig strand G	335..338	CDD:409353	1/2 (50%)
		Ig4_L1-NrCAM_like	347..434	CDD:409367	22/100 (22%)
		Ig strand B	363..367	CDD:409367	0/3 (0%)
		Ig strand C	376..380	CDD:409367	0/3 (0%)
		Ig strand E	399..403	CDD:409367	0/3 (0%)
		Ig strand F	413..418	CDD:409367	2/4 (50%)
		Ig strand G	426..429	CDD:409367	1/3 (33%)
		Ig	447..524	CDD:416386	22/95 (23%)
		Ig strand A'	447..451	CDD:409353	1/3 (33%)
		Ig strand B	454..463	CDD:409353	4/8 (50%)
		Ig strand C	469..474	CDD:409353	1/5 (20%)
		Ig strand C'	477..480	CDD:409353	0/2 (0%)
		Ig strand D	485..490	CDD:409353	2/4 (50%)
		Ig strand E	491..498	CDD:409353	1/12 (8%)
		Ig strand F	505..513	CDD:409353	2/7 (29%)
		Ig strand G	516..524	CDD:409353	3/19 (16%)
		Ig	528..627	CDD:416386	23/113 (20%)
		Ig strand A	528..534	CDD:409353	1/5 (20%)
		Ig strand A'	537..542	CDD:409353	2/4 (50%)
		Ig strand B	545..553	CDD:409353	1/7 (14%)
		Ig strand C	564..568	CDD:409353	0/3 (0%)
		Ig strand D	583..586	CDD:409353	0/2 (0%)
		Ig strand E	589..593	CDD:409353	1/3 (33%)
		Ig strand F	602..609	CDD:409353	1/6 (17%)
		Ig strand G	616..620	CDD:409353	1/3 (33%)
		FN3	627..716	CDD:238020	4/18 (22%)
		fn3	730..811	CDD:394996
		FN3	832..926	CDD:238020
		FN3	931..1026	CDD:238020
		Bravo_FIGEY	1120..1201	CDD:404722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100