DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and zgc:152904

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001070212.1	Gene:	zgc:152904 / 767777	ZFINID:	ZDB-GENE-060929-856	Length:	809	Species:	Danio rerio

Alignment Length:	435	Identity:	111/435 - (25%)
Similarity:	185/435 - (42%)	Gaps:	67/435 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILNLAALTAVAWANHHESLSLSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHKGR 71
            :|::...:..|.|::.||::.:              .|...||||:|..:|   ||..| ||..:
Zfish   179 VLSVPQQSFNATADYQESVTFT--------------CVTSGSPDPQVTWYW---KGHAI-EHSEQ 225

  Fly    72 IHIEQTSTEQLKIVFAHIALADKGNWSCEAAD--GSLHSKSF-DLIVYQKITFTENATVMTVKEG 133
            ..:...:..:..:...:|...|.|.:.|.|::  ||..|:.| .:.|...||...|.|.:   ||
Zfish   226 YVLNTMNGGKSTLTVKNIKQTDGGPYMCRASNKAGSSESQLFLKVFVQPHITQLRNVTAV---EG 287

  Fly   134 EKATILCEVKGEPQPNVTWHFNGQPISAGAADDSKFRILADG------------LLINKVTQNDT 186
            ..|.|.|..:|||.|.::|.......|....:.||     ||            |.|:.|..:|.
Zfish   288 SAAMISCTAEGEPLPEISWRRASDGHSFTDGEKSK-----DGRVEVRGRHGKSMLTISGVQLSDW 347

  Fly   187 GEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTW 251
            |.:.|.|  ::.|..  .::::.:.||:.|.:....  |:.|::......:.||..:.|.|...|
Zfish   348 GRFDCEA--LSRIGG--HQKSMFLDIEYAPKFQTNQ--SIFYSWEGNPVNISCEVKSNPAATMLW 406

  Fly   252 YRKHNKLH----SNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKP 312
            .|:...:.    ||.|:::....|.   |.:..::...|..|.|.|||::|...:...|.|.:.|
Zfish   407 RRERFTISSQGTSNIRIHSTDGRSL---LEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVP 468

  Fly   313 PSPANFQLRGFNSNTFDVVLSAPRGPPDSPMGVN-GFRIEYMTEMEFKTDAGKWTNARRKDYAFE 376
            .||.:.::...:.....|...    .|||..||. .|   |:......:.|.:|.:||.....
Zfish   469 SSPYSVRMTAVSQRMATVSFM----KPDSHGGVPISF---YIINYRDTSSAQEWRSARTHGVQ-- 524

  Fly   377 EGATFLLTNLEPDTVYLVRAASRNLAGFSDFTKVEKYKTLSL-EP 420
              ...:||:|||:|.|.||.::.|..|..:|:..|.::||.: ||
Zfish   525 --TAVVLTSLEPNTTYEVRVSAVNGKGQGEFSHTESFQTLPIREP 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	21/84 (25%)
		I-set	128..202	CDD:254352	23/85 (27%)
		Ig	133..>193	CDD:299845	20/71 (28%)
		IG_like	228..307	CDD:214653	19/82 (23%)
		Ig	235..305	CDD:143165	18/73 (25%)
		FN3	312..415	CDD:238020	28/103 (27%)
zgc:152904	NP_001070212.1	Ig	1..81	CDD:299845
		IG_like	2..80	CDD:214653
		IGc2	97..158	CDD:197706
		Ig	177..273	CDD:299845	26/111 (23%)
		I-set	184..270	CDD:254352	25/103 (24%)
		Ig	272..369	CDD:299845	28/108 (26%)
		I-set	274..367	CDD:254352	27/104 (26%)
		IG_like	385..462	CDD:214653	18/79 (23%)
		IGc2	386..454	CDD:197706	17/70 (24%)
		FN3	468..561	CDD:238020	28/103 (27%)
		fn3	<591..650	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010