DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and igsf9bb

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	284	Identity:	70/284 - (24%)
Similarity:	112/284 - (39%)	Gaps:	63/284 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DP----KVELHWKSPKGEIIREHKGRIHIEQTSTEQLKIVFAHIALADKGNWSC-----EAADGS 105
            ||    :..||.||           .:.||:..:|            |:|.:.|     |....:
Zfish    81 DPEYAGRASLHGKS-----------SLRIERVRSE------------DQGWYECKVLMLEQQYHT 122

  Fly   106 LHSKSF-DLIVYQKITFTEN-ATVMTVKEGEKATILCEVKGEPQPNVTWHFNGQPISAGAADDSK 168
            .|:.|: .|.|....|||:. ...:..|||...|:.|...|.|:|:|:|...|.|:.    |.:|
Zfish   123 FHNGSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPVQ----DSTK 183

  Fly   169 FRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQE--RTVLMKIEHKP-IWSKTPFVSLKYAY 230
            :::....|.:..:::.|.|.|.||||      |:..|  .|..:.::..| |.|....:::.
Zfish   184 YKVSDGSLTLVSISREDRGAYTCRAY------SEQGEAVHTTRLLVQGPPFIVSPPENITVN--- 239

  Fly   231 INGTATLMCEALAEP-PANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRAR 294
            |:..|...|:|.|.| ...:||:.:.:.:...|.|....|.....||.|..:.......|.|...
Zfish   240 ISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPS 304

  Fly   295 NDLGTIERTTRLEQGEKPPSPANF 318
            |.||            :|||.:.:
Zfish   305 NSLG------------RPPSASAY 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	16/74 (22%)
		I-set	128..202	CDD:254352	22/73 (30%)
		Ig	133..>193	CDD:299845	17/59 (29%)
		IG_like	228..307	CDD:214653	19/79 (24%)
		Ig	235..305	CDD:143165	18/70 (26%)
		FN3	312..415	CDD:238020	3/7 (43%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	12/54 (22%)
		Ig	41..113	CDD:143165	12/54 (22%)
		IG_like	144..223	CDD:214653	25/88 (28%)
		IGc2	151..208	CDD:197706	18/60 (30%)
		I-set	227..319	CDD:254352	25/105 (24%)
		Ig	<263..319	CDD:299845	14/66 (21%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100