DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and igsf9ba

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	338	Identity:	89/338 - (26%)
Similarity:	124/338 - (36%)	Gaps:	86/338 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 ENATVMTVKEGEKATILCEV----KGEPQPNVT-WHFNGQPIS----------------AGAAD- 165
            |....:|.:.||...:.|:|    .|:..|.|. |...|.||.                ||.|.
Zfish    28 EEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASL 92

  Fly   166 DSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQERT------VLMKIEHKPIWSKTP-- 222
            ..|     ..|.|.:|...|.|.|.||...:     :.|..|      |.:.:...|.:|.||
Zfish    93 HGK-----ASLQIEQVRSEDQGWYECRVLML-----EQQYDTFHNGSWVHLTVNAPPTFSDTPPQ 147

  Fly   223 FVSLKYAYINGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFD 287
            :|.   |...|:.||.|.|...|....||.|:.::| ::.|.||: ||   .|||:..:......
Zfish   148 YVE---AREGGSITLTCTAFGNPKPVVTWLREGDQL-TSTRKYTV-SD---GSLTVQAITREDRG 204

  Fly   288 NYRCRARNDLGTIERTTR-LEQGEKPP----SPANFQLRGFNSNTFDVVLSAPRG--------PP 339
            .|.|||.:|.|....||| |.||  ||    .|.|..:....:..|.....|..|        ..
Zfish   205 AYSCRAHSDQGEALHTTRLLVQG--PPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEE 267

  Fly   340 DS-----------PMGVNGFRIEYMTEMEFKTDAGKWTNARRKDYAFEEGATFLLT--------N 385
            |:           .:.::|..|.|..:.|   ||||:|.:..........|:..||        |
Zfish   268 DNVYFKNDLKLRVRIFIDGTLIIYRVKPE---DAGKYTCSPSNSLGISPSASAYLTVQYPARVVN 329

  Fly   386 LEPDTVYLVRAAS 398
            : |..:|:.|..|
Zfish   330 M-PPVIYVPRKLS 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653
		I-set	128..202	CDD:254352	24/95 (25%)
		Ig	133..>193	CDD:299845	22/81 (27%)
		IG_like	228..307	CDD:214653	28/79 (35%)
		Ig	235..305	CDD:143165	24/69 (35%)
		FN3	312..415	CDD:238020	25/118 (21%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	23/89 (26%)
		I-set	139..225	CDD:254352	33/93 (35%)
		I-set	229..321	CDD:333254	18/94 (19%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900