Protein Alignment fipi and robo4

DIOPT Version :9

• Sequence 1: NP_787975.1
• Gene: fipi / 33676
• FlyBaseID: FBgn0031627
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_689255.3
• Gene: robo4 / 560765
• ZFINID: ZDB-GENE-020809-1
• Length: 1134
• Species: Danio rerio
• Alignment Length: 478
• Identity: 111/478 - (23%)
• Similarity: 171/478 - (35%)
• Gaps: 134/478 - (28%)

  Fly     2 RLIGFILNLAALTAVAWANHHESLSLSPAEHSVVRYTNESLIVQCR---SPDPKVELHWKS---- 59
            ||:..| ||..:.      ||.|        .||........:.||   :|:|.::  |..
Zfish    63 RLVSEI-NLPRIV------HHPS--------DVVVRVGSPATLSCRAEGNPEPTIQ--WLRNGQP 110

  Fly    60 ---------------PKG-----EIIREHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADG 104
                           |.|     .::...||:.|         :.|:|.||....||  ..:.:.
Zfish   111 LDTDKMDAQSQPIVLPDGSLFFFSVVPGRKGQSH---------EAVYACIAHNSIGN--ATSRNA 164

  Fly   105 SLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVK-GEPQPNVTWHFNGQPISAGAADDSK 168
            |||      |...:..|....:.:.|..||.|||.|... |.|:|||||..:|..|:   :.:..
Zfish   165 SLH------IAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEPNVTWRKDGILIN---SSNEH 220

  Fly   169 FRILADGLLINKVTQNDTGEYACRAYQVNSIASDM----QERTVLMKIEHKPIWSKTP-FVSLKY 228
            :..|...|:|....:||:|.|:|       |||:|    :.|...:.:..||:..:.| .||::
Zfish   221 YTELKGKLIIAPAQKNDSGVYSC-------IASNMIGVRESRAARLSVLAKPVLLRKPEDVSVQ- 277

  Fly   229 AYINGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRA 293
              :..:|...|||..:|..:..|.|:...| .|.| |.|..|   .||.||.:.......|.|..
Zfish   278 --LGESAQFFCEADGDPMPSIEWSREQGPL-PNGR-YLINPD---HSLQIHYVTAQDMGRYSCTV 335

  Fly   294 RNDLGT--------IERT--TRLEQGEKPPSPANFQLRGF----NSNTFDVVLSAPRGPPDSPMG 344
            .|.||.        :|..  |||....|..|.....|...    .::....|:...:.....|..
Zfish   336 ENKLGVSVASAQLLVEDAGGTRLRDLHKELSALRVSLENVTVMSTASNMSQVMWKLQSFGSQPHY 400

  Fly   345 VNGFRIEYMTEMEFKTDAGKWTNAR-------------RKDYAFE-----EGATF---------- 381
            :.||.:.|.:.:...:|   ||..|             ::.|.:|     .|::.
Zfish   401 LEGFEVLYRSLLPASSD---WTAQRVPQPSLHTHVGPLKRGYKYEFKVRPYGSSLYGRESNTRHL 462

  Fly   382 ----LLTNLEPDTVYLVRAASRN 400
                ::.:..|..|.:...|.||
Zfish   463 RVPEIVPSAAPQDVSITMPAERN 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	21/108 (19%)
		I-set	128..202	CDD:254352	26/74 (35%)
		Ig	133..>193	CDD:299845	23/60 (38%)
		IG_like	228..307	CDD:214653	25/88 (28%)
		Ig	235..305	CDD:143165	23/79 (29%)
		FN3	312..415	CDD:238020	19/125 (15%)
robo4	XP_689255.3	Ig1_Robo	70..169	CDD:143317	25/131 (19%)
		I-set	71..168	CDD:254352	24/129 (19%)
		I-set	175..261	CDD:254352	30/95 (32%)
		Ig2_Robo	177..261	CDD:143201	29/93 (31%)
		I-set	265..350	CDD:254352	26/92 (28%)
		Ig	282..350	CDD:299845	22/72 (31%)
		FN3	373..448	CDD:214495	11/77 (14%)
		FN3	472..560	CDD:238020	5/14 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900