DRSC/TRiP Functional Genomics Resources

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Protein Alignment fipi and lrit3a

DIOPT Version :9

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001122166.1 Gene:lrit3a / 558559 ZFINID:ZDB-GENE-080723-63 Length:636 Species:Danio rerio


Alignment Length:386 Identity:70/386 - (18%)
Similarity:117/386 - (30%) Gaps:134/386 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 KITFTENATVMTVKEGEKATILCEVKGEPQPNVTWH------FNGQPISAGAADDSKFRILADGL 176
            |.|...:||.:|...|....:.|:..|.|.|.:.|.      .|...:.....:..::.||:   
Zfish   251 KPTVMTSATKITSPLGSNVLLRCDANGFPTPTLLWTTADGSVVNNTVVQESPGEGVRWSILS--- 312

  Fly   177 LINKVTQNDTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEA 241
             ::.:...|.|:|.|:|..|...|    |..:.:.::  .:...|||                  
Zfish   313 -LHSIVFKDAGDYRCKAKNVAGNA----EAYITLSVD--GVQPTTPF------------------ 352

  Fly   242 LAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRL 306
               ||.|.|...:...                         |:.|...:......|..|..|||.
Zfish   353 ---PPINITKQPEDQP-------------------------TTTFTPTKMPLFTSLSPITITTRP 389

  Fly   307 EQGEKPP---------------------SPANFQ-------------LRGF-----NSNTFDVVL 332
            .....||                     .||..|             :|..     .:.|..::.
Zfish   390 VMTTMPPLTTRKSPIPGGGVQRSPPAGDKPAKVQQSKNGKGSIKKSDIRDIEVVEETTETAVLLW 454

  Fly   333 SAPRGPPDSPMGVNGFRIEYMTEME-FKTDAGKWTNARRKDYAFEEGATFLLTNLEPDTVYLVRA 396
            ||...|.|:|:.|..|..:...:.| ..|:.|:              ...||..|.|:.||.|..
Zfish   455 SAEGLPSDTPLTVVYFPYDAKDDKETVDTEVGQ--------------GKLLLEYLMPNQVYTVCL 505

  Fly   397 ASRNLAGFSDFTKVEKYKTLSLEPRVSSGVKETRN--------MCVELGVMTLMVLMRPFL 449
            .:::    |...:...:.||.:      |.:|.:|        :...:.|..::||:...|
Zfish   506 VTKS----SGKEQCVDFSTLEI------GGEEGQNKVLMIASAIACAIAVPLIVVLLYKIL 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653
I-set 128..202 CDD:254352 17/79 (22%)
Ig 133..>193 CDD:299845 13/65 (20%)
IG_like 228..307 CDD:214653 11/78 (14%)
Ig 235..305 CDD:143165 9/69 (13%)
FN3 312..415 CDD:238020 25/142 (18%)
lrit3aNP_001122166.1 LRR_8 81..141 CDD:290566
leucine-rich repeat 83..106 CDD:275378
LRR_4 107..145 CDD:289563
leucine-rich repeat 107..130 CDD:275378
LRR_8 129..>171 CDD:290566
LRR_4 129..170 CDD:289563
leucine-rich repeat 131..154 CDD:275378
leucine-rich repeat 155..168 CDD:275378
TPKR_C2 199..249 CDD:301599
Ig 252..343 CDD:299845 21/98 (21%)
IG_like 261..343 CDD:214653 18/89 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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