DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and iglon5

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	300	Identity:	71/300 - (23%)
Similarity:	124/300 - (41%)	Gaps:	30/300 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LAALTAVAW--ANHHESLSLSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIR-----E 67
            ||.|.|:.|  .:..::........::.....||::::|:..:......|.:....:..     .
Zfish    10 LALLLALLWKGPSGAQAAEFGHLPDNITVLEGESVVLRCKIDEEVTHKAWLNRSNILFTGTDKWS 74

  Fly    68 HKGRIHIEQTSTEQLKIVFAHIALADKGNWSCE-AADGSLHSKSFDLIVYQKITFTENATVMTVK 131
            ...|:.:|..:.....|....:.:||:|.::|. .|.....:....|||.........:...:|.
Zfish    75 LDSRVSLENNNNSDFSIRIERVMVADEGPYTCSFQARNKPRTAHVYLIVQVPARIVNISQDKSVN 139

  Fly   132 EGEKATILCEVKGEPQPNVTWHFNGQPISAGAADDSKFRILADG--LLINKVTQNDTGEYACRAY 194
            |||...:.|...|.|:|.:||            .|.|:.:|.:|  |.|.::.::...::.|
Zfish   140 EGEDVNLFCLAVGRPEPTITW------------KDFKYGLLNEGEFLEITEIKRHQAEDFEC--- 189

  Fly   195 QVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTWYRKHNK-L 258
            ..|:..:....|.|.:.:.:.||.:.   |....|.:..||.|.|||:|.|.|:|.|||...: :
Zfish   190 ITNNGVAPPDTRKVKVTVNYPPIITD---VKNMPAQVGKTAILRCEAMAVPTASFEWYRDDRRPV 251

  Fly   259 HSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLG 298
            .|:|.| .|:::...|.|....:....|.||.|.|.|.||
Zfish   252 ESDNTL-KIKNEKTRSLLLFTNVTEKHFGNYTCFASNRLG 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	13/87 (15%)
		I-set	128..202	CDD:254352	18/75 (24%)
		Ig	133..>193	CDD:299845	15/61 (25%)
		IG_like	228..307	CDD:214653	27/71 (38%)
		Ig	235..305	CDD:143165	25/64 (39%)
		FN3	312..415	CDD:238020
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	13/89 (15%)
		Ig	35..123	CDD:299845	13/87 (15%)
		Ig	125..>183	CDD:299845	16/69 (23%)
		I-set	128..207	CDD:254352	20/93 (22%)
		IG_like	217..298	CDD:214653	27/74 (36%)
		ig	223..296	CDD:278476	26/68 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840