back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fipi and SDK2

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001138424.1	Gene:	SDK2 / 54549	HGNCID:	19308	Length:	2172	Species:	Homo sapiens

Alignment Length:	439	Identity:	98/439 - (22%)
Similarity:	187/439 - (42%)	Gaps:	63/439 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ALTAVAWANHHESLSLSPAEHSVVRYTNESLIVQCR-SPDPKVELHWKSPKGEIIREHKGRIHIE 75
            |:|::|     .:::..|.:.:|:  ...|:::.|. |..|:..:.|:  |||.|.. .|.:.:.
Human   396 AVTSIA-----PNITRGPLDSTVI--DGMSVVLACETSGAPRPAITWQ--KGERILA-SGSVQLP 450

  Fly    76 Q-TSTEQLKIVFAHIALADKGNWSCEAADG-SLHSKSFDLIVYQKITFTENATVMTVKEGEKATI 138
            : |..|...::.:...::|.|.::|.|.:. .:...|.||:|:.:...|:.....:|.:|.:|::
Human   451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASM 515

  Fly   139 LCEVKGEPQPNVTWHFNGQPISAGAADDSKFRILADGLL-INKVTQNDTGEYACRAYQVNSIASD 202
            :|.|..:|:..:.:.:.....:.|.....:.|:..:|.| |::....|.|.|.||...    |..
Human   516 VCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVIS----AGG 576

  Fly   203 MQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTWYRKHN----------K 257
            ...|:..:::...|...:.|..:|        :|:...|:     |.||.:..:          :
Human   577 NDSRSAHLRVRQLPHAPEHPVATL--------STVERRAI-----NLTWTKPFDGNSPLIRYILE 628

  Fly   258 LHSNNRLYTI---QSDSYWSSLTIHVLNTSAFDNYRCRARNDLGT---IERTTRLEQGEKPPS-- 314
            :..||..:|:   ..|...:|:|:..|..:....:|..|.||:|.   .:.|.|:...|:||:
Human   629 MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAP 693

  Fly   315 PANFQLRGFNSNTFDVVLSAPRGPPDSPMG--VNGFRIEYMTEMEFKTDAGKWTNARRKDYAFEE 377
            |.|....|   .|...::...:.||:|...  :.|:.|.|..       ||.....:.|:....:
Human   694 PQNVIASG---RTNQSIMIQWQPPPESHQNGILKGYIIRYCL-------AGLPVGYQFKNITDAD 748

  Fly   378 GATFLLTNLEPDTVYLVRAASRNLAGFSDF-TKVEKYKTLSLEPRVSSG 425
            ....||.:|...|.|.:..|:.|.||...: :||.:: ||...|.|..|
Human   749 VNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW-TLQGVPTVPPG 796

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.