DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and dpr12

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	73/337 - (21%)
Similarity:	110/337 - (32%)	Gaps:	155/337 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 ENATVM----TVKEGEKATILCEVKGEPQPNVT-----------WHFNGQPISAGA---ADDSKF 169
            |::.:|    ||:.|..|.::|:|.|..:..|.           ||.    :|:||   .:|.:|
  Fly    78 EDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHI----LSSGAQLYTNDERF 138

  Fly   170 RIL-ADG-----LLINKVTQNDTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKY 228
            .|| ..|     |.|..|.:.|.|.|.|:......|            |.|        ||:|:.
  Fly   139 AILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGI------------ISH--------FVNLQV 183

  Fly   229 ----AYING----------TATLMC--EALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLT 277
                |:|.|          |..|:|  |....||....|.:       |:||.
  Fly   184 VVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQK-------NDRLI------------ 229

  Fly   278 IHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRGFNSNTFDVVLSAPRGPPDSP 342
                      || ..:|.|: |||.|         |.|.. |.|        :::..|:
  Fly   230 ----------NY-VDSRRDI-TIETT---------PGPRT-QSR--------LIIREPQ------ 258

  Fly   343 MGVNGFRIEYMTEMEFKTDAGKWTNARRKDYAFEEGATFLLTNLEPDTVYLVRAASRNLAGFSDF 407
                            .||:|.:|.:              .:|.||.::|:..:...|:|..|
  Fly   259 ----------------VTDSGNYTCS--------------ASNTEPASIYVFVSKGDNMAAIS-- 291

  Fly   408 TKVEKYKTLSLE 419
                :.||.|.:
  Fly   292 ----RRKTSSAD 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653
		I-set	128..202	CDD:254352	27/97 (28%)
		Ig	133..>193	CDD:299845	23/79 (29%)
		IG_like	228..307	CDD:214653	21/94 (22%)
		Ig	235..305	CDD:143165	17/71 (24%)
		FN3	312..415	CDD:238020	16/102 (16%)
dpr12	NP_652462.3	IG	86..183	CDD:214652	31/120 (26%)
		Ig_3	193..271	CDD:404760	27/162 (17%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	1/11 (9%)
		Ig strand F	264..269	CDD:409353	1/18 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900