DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fipi and klg

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	81/415 - (19%)
Similarity:	167/415 - (40%)	Gaps:	71/415 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HSVVRYTNESLIVQCRSPDPKVE------LHWKSPKGEIIREHKGRIHIEQTSTEQLKIV----- 85
            |:......::|::.|     :||      |.|:.....:...     :|..|..|:::::
  Fly   108 HTYRAVVGDTLVLPC-----QVENLGNFVLLWRRGTNVLTAS-----NIMVTRDERVRLIDGYNL 162

  Fly    86 -FAHIALADKGNWSCEAAD----GSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKGE 145
             .:.:...|.|::.|:.:|    ..:|  :.:::|...:.....:..:..::|...|:.|:..|.
  Fly   163 EISDLEPQDAGDYVCQISDKINRDQVH--TVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGN 225

  Fly   146 PQPNVTWHFNGQPISAGAADDSKFRILADG--LLINKVTQNDTGEYACRAYQVNSIASDMQERTV 208
            |.|::.|      .....|:.|..|| .||  |.:.|:.:...|.|.|.|  .|.:...:   ||
  Fly   226 PVPSIYW------TKKSGANKSTARI-GDGPILTLEKLERQQAGVYQCTA--DNGVGDPV---TV 278

  Fly   209 LMKIEHKPIWSKTPFVSLKYAYING----TATLMCEALAEPPANFTWYRKHNKLHS-NNRLYTIQ 268
            .|:::    ....|.:.::.::|:.    .|.|:|...|:|.|..:||:....:.| :.|:...:
  Fly   279 DMRLD----VLYPPDIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATR 339

  Fly   269 SDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQLR--GFNSNTFDVV 331
            ::.:  .|||..:....|.||.|.|.|.||   |:.:..:....|..|.|...  |.:.:::::.
  Fly   340 ANRH--MLTIRHIQQEDFGNYSCVADNSLG---RSRKYMELSGRPGAAEFYSPKWGRSPDSYNLT 399

  Fly   332 LSAPRGPPDSPMGVNGFRIEYMTEMEFKT--DAGKW------TNARRKDYAFEEGATFLLTNLEP 388
            ......||     :...|:.|......:|  ..|:|      ...|..........::.:.||.|
  Fly   400 WKIDSYPP-----LEEVRLLYRRVQMNETYQQPGRWHDFILTPEHRPASEPLTHIMSYTIKNLHP 459

  Fly   389 DTVYLVRAASRNLAGFSDFTKVEKY 413
            ...|.....::|..|:::.:.:.::
  Fly   460 GGYYEAIVQAKNRYGWNEVSDIFQF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	14/97 (14%)
		I-set	128..202	CDD:254352	20/75 (27%)
		Ig	133..>193	CDD:299845	18/61 (30%)
		IG_like	228..307	CDD:214653	23/83 (28%)
		Ig	235..305	CDD:143165	22/70 (31%)
		FN3	312..415	CDD:238020	18/112 (16%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	3/20 (15%)
		IG_like	109..195	CDD:214653	14/97 (14%)
		Ig	118..191	CDD:143165	14/84 (17%)
		IG_like	205..274	CDD:214653	20/77 (26%)
		IGc2	213..273	CDD:197706	20/68 (29%)
		IGc2	301..367	CDD:197706	19/67 (28%)
		FN3	392..486	CDD:238020	14/98 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442848
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740