DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and dpr11

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	48/211 - (22%)
Similarity:	75/211 - (35%)	Gaps:	33/211 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 MTVKEGEKATILCEVKGEPQPNVTW--HFNGQPISAGAA---DDSKFRILAD-----GLLINKVT 182
            :|.:.|..|.:.|.||.....:|:|  ..:|..::...|   .|.:|..:..     .|.|..|.
  Fly   127 VTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQ 191

  Fly   183 QNDTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMC--EALAEP 245
            ..|.|.|.|:......:::.:|.:.|:.:.|   |..:..    :|........|.|  ....||
  Fly   192 ARDAGSYECQVSTEPKVSARVQLQVVVPRTE---ILGEPD----RYVKAGSNVVLRCIVRGALEP 249

  Fly   246 PANFTWYRKHNKLHSNNRLYTIQSD-----------SYWSSLTIHVLNTSAFDNYRCRARND-LG 298
            |....||....:|.:::|.:..|.|           |...||.|.........||.|...|. ..
  Fly   250 PTFIMWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSNSPSA 314

  Fly   299 TIERTTRLEQGEKPPS 314
            |:  |..:..||...|
  Fly   315 TV--TLNIINGESSAS 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653
		I-set	128..202	CDD:254352	19/83 (23%)
		Ig	133..>193	CDD:299845	18/69 (26%)
		IG_like	228..307	CDD:214653	22/92 (24%)
		Ig	235..305	CDD:143165	21/83 (25%)
		FN3	312..415	CDD:238020	1/3 (33%)
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	20/88 (23%)
		Ig	127..217	CDD:299845	20/89 (22%)
		IG_like	227..320	CDD:214653	22/98 (22%)
		IGc2	234..311	CDD:197706	18/76 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900