DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and ImpL2

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	56/266 - (21%)
Similarity:	99/266 - (37%)	Gaps:	50/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EHKGRIHIEQTSTEQLKIVFAHIA--------LADKGN---WSCEAADGSLHSKSFDLIVYQKIT 120
            |.|..:|:...:.    ::|..||        |.|..|   .|.||.:....:::|:.   ..:.
  Fly     2 EAKMNLHVCALAL----LLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEA---DWLK 59

  Fly   121 FTEN-ATVMTVKEGEKATILCEVKGEPQPNVTWHFNGQPIS----------AGAADDSKFRILAD 174
            ||:. .|.:...:|....|:||:.|...|::.|.....|.|          |..|..:..|:.:.
  Fly    60 FTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSS 124

  Fly   175 GLLINKVTQNDTGEYAC--RAYQVNSIASDM----------QERTVLMKIEHKPIWSKTPFVSLK 227
            .::.:.:::..|  |.|  |.......||.:          .|:|.....:.:.|:::...:.|
  Fly   125 HIIDHVLSEART--YTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL- 186

  Fly   228 YAYINGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCR 292
               :.....|.|...|.|.|..||....||.......:.:.::   ..|.|..:......||:|.
  Fly   187 ---MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN---GDLLISEIKWEDMGNYKCI 245

  Fly   293 ARNDLG 298
            |||.:|
  Fly   246 ARNVVG 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	13/58 (22%)
		I-set	128..202	CDD:254352	17/85 (20%)
		Ig	133..>193	CDD:299845	15/71 (21%)
		IG_like	228..307	CDD:214653	18/71 (25%)
		Ig	235..305	CDD:143165	18/64 (28%)
		FN3	312..415	CDD:238020
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	17/66 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900