DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and dpr20

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	52/268 - (19%)
Similarity:	92/268 - (34%)	Gaps:	71/268 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 EQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKATIL 139
            ::|....|..:|...:.|:|.:.         |.:.:. ..::.:.....||.:||:.|....:.
  Fly   236 QKTDAPMLNYIFDTFSSANKHHH---------HDQRYG-PHFEDVQRIGQATNLTVQAGSSIHLN 290

  Fly   140 CEVKGEPQPNVTW-HFNGQPISAGAADDSKFRILADG---------------------LLINKVT 182
            |.:.......|:| ..|.|  ..|..:.:...:|..|                     |.|..|.
  Fly   291 CRISLLQDKTVSWVRHNTQ--DEGKDNGNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLKITNVK 353

  Fly   183 QNDTGEYAC-------RAYQVN------------SIASDMQER------TVLMK--IEHKPIWSK 220
            ::|...|.|       |..|:|            .:...:||:      |:.:.  :.:..:.|.
  Fly   354 KDDEAIYECQISTHPPRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSS 418

  Fly   221 TPFVS-----LKYAYINGTATLMCEALAEPPANFTW-YRKHNKLHSNNRLYTIQSDSYWS-SLTI 278
            ..|..     |.|....|..::..| |.|..||.|. ..|.:|..|.|  ||.....:.: ::.:
  Fly   419 VVFWKHMDNILNYDVTRGGVSVKTE-LMEDGANSTLSIAKISKTDSGN--YTCSISEFQNFTIVV 480

  Fly   279 HVLNTSAF 286
            |:||..:|
  Fly   481 HILNGESF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	6/39 (15%)
		I-set	128..202	CDD:254352	20/114 (18%)
		Ig	133..>193	CDD:299845	15/88 (17%)
		IG_like	228..307	CDD:214653	18/61 (30%)
		Ig	235..305	CDD:143165	16/54 (30%)
		FN3	312..415	CDD:238020
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	17/88 (19%)
		Ig	279..378	CDD:299845	20/100 (20%)
		Ig	400..471	CDD:299845	18/73 (25%)
		IG_like	402..480	CDD:214653	18/80 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900