DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and CG13506

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	90/503 - (17%)
Similarity:	169/503 - (33%)	Gaps:	165/503 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NLAALTAVAWANHHESLS--LSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHKGR 71
            |.....||.|..:...::  .:|....|....|.|::::..||:...:.:.     ||:.:.
  Fly    95 NFQLSNAVVWYKNRIIIANGQNPISQRVQCMLNNSILLRNVSPEDSDDYYC-----EILPQR--- 151

  Fly    72 IHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKA 136
                         |..|.||......|....|..:..:|                 .|.::|:..
  Fly   152 -------------VRQHTALRVGARLSILCDDRDITDRS-----------------QTFRQGDHH 186

  Fly   137 TILCEVKGEPQPNVTWHF---NGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNS 198
            .:.|.........:.|.|   ||||.|.    |::..:    ::::.|.:.:.|:|.|
  Fly   187 KLECRTYLPDNATIKWSFNDLNGQPSSV----DNQNGV----IILDNVDEKNAGDYQC------- 236

  Fly   199 IASDMQER----TVLMKIEHKPIWSKTPFVSLKYAYIN----GTATLMCEALAEPPANFTWYRKH 255
            :|.|....    ||.:.:::.||      ||.....:|    .||.|.|...|:|... :::.|.
  Fly   237 LADDGSRHPPHGTVHIDVQYSPI------VSTHRHNVNTEKGATAELYCNYRAKPIGR-SYFIKD 294

  Fly   256 NKLHSNNRLY----TIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSP- 315
            .|....:..|    ::.:|...::|.:..:..|....|.|:..|.:|:.|  .::.....|.:|
  Fly   295 GKTLQLSDKYSLKDSVHNDHNRTTLIVREVTDSDLGEYLCQVENAIGSNE--VKVHVSYNPETPQ 357

  Fly   316 ---------------------------ANFQLRG-FNSNTFDVVLSAPRGPPDSPMGVNGFRIEY 352
                                       .::||.| :..:|..|:.:......|     |.::|.:
  Fly   358 FEDMTVEGNKVTLHWLVRSHQLLSEAMLDYQLTGSYTWSTVQVLETHRHNNTD-----NIWKITH 417

  Fly   353 MTEMEFKTDAGKWTNARRKDYAFEEGATFLLTNLEPDTVYLVRAASRNLAGFSDF---------- 407
            ..|:    ..|.| :||.|                          ::|..|:|.|
  Fly   418 QLEL----SRGVW-HARVK--------------------------TKNTKGWSHFSNDHVFEIPE 451

  Fly   408 -TKVEKYKTLSLEP---------RVSSGVKETRNMCVELGVMTLMVLM 445
             ::|:|.:.:.|.|         .:|.|...:... :.:||:.|..|:
  Fly   452 DSEVDKDEEVELPPDEIVQAGIMPMSKGAASSMQR-LNVGVILLAALL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	14/81 (17%)
		I-set	128..202	CDD:254352	16/76 (21%)
		Ig	133..>193	CDD:299845	14/62 (23%)
		IG_like	228..307	CDD:214653	18/86 (21%)
		Ig	235..305	CDD:143165	16/73 (22%)
		FN3	312..415	CDD:238020	22/142 (15%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	10/55 (18%)
		IGc2	83..146	CDD:197706	10/55 (18%)
		IG_like	176..254	CDD:214653	20/109 (18%)
		Ig	176..239	CDD:299845	16/94 (17%)
		I-set	258..349	CDD:254352	22/99 (22%)
		Ig	275..348	CDD:143165	16/75 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830