DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fipi and wrapper

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	92/429 - (21%)
Similarity:	170/429 - (39%)	Gaps:	86/429 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHKGRIHIEQTSTEQL------KIVFAHIAL 91
            :|..|.|:::.:.|....|...:.|......::...    |.|....:::      .:..|::..
  Fly    43 TVKTYENDTVQLPCTLNTPFRYVRWHRDDVALVDSR----HPELPPPDRIMLWPNGSLQVANVQS 103

  Fly    92 ADKGNWSCEAADGSLHSKSFDLIVYQKITFTENATVMTVKE--------GEKATILCEVKGEPQP 148
            :|.|::.||....|.|      :|.|.....:.|..:.::.        |....::||.:|.|||
  Fly   104 SDTGDYYCEMNSDSGH------VVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQP 162

  Fly   149 NVTWHFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQERTVLMKIE 213
            .:||..||..|...:...::     ..|::...::|..|...|       :||:......:..:.
  Fly   163 VITWRLNGNVIQPQSNTGNR-----QSLILEIKSRNQAGLIEC-------VASNGVGEPAVANVY 215

  Fly   214 HKPIWSKTPFVSLK----YAYINGTATLMCEALAEPPANFTWYR--------KHNKLHSNNRLYT 266
            ...::|  |.||:.    |..:...|.|.|...|.|.|...|:.        .|:..| .:.|.|
  Fly   216 LHVLFS--PEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTH-ESELQT 277

  Fly   267 IQSDSYWSSLTIHVLNTSAFDN-----YRCRARNDL----GTIERTTRLEQGEKPPSPANFQLR- 321
            .:|..::.:...|:|...:..|     |.|||.|.:    |::|.|.|       |.|..|::.
  Fly   278 NRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGR-------PMPCLFKINP 335

  Fly   322 GFNSNTFDVVLSAPRGPPDSPMGVNGFRIEYM------TEMEFKTDAGKWTNARRKDYAFEEG-- 378
            |..|:|..|::    ...:|.:.:..|::::.      ...:.:|:   ||.......| ..|
  Fly   336 GTQSSTSHVLV----WQTESLLPIMEFKLKFRQIPSNNVTRQVRTN---WTELTIPAQA-TNGLI 392

  Fly   379 --ATFLLTNLEPDTVYLVRAASRNLAGFSDFTKVEKYKT 415
              .|:.|..|:|.::|.|...:||..|:||.:|:.::.|
  Fly   393 YITTYTLHGLQPASLYEVSVLARNSFGWSDNSKIVRFAT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	15/87 (17%)
		I-set	128..202	CDD:254352	17/81 (21%)
		Ig	133..>193	CDD:299845	16/59 (27%)
		IG_like	228..307	CDD:214653	25/95 (26%)
		Ig	235..305	CDD:143165	23/86 (27%)
		FN3	312..415	CDD:238020	26/113 (23%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	16/90 (18%)
		IG_like	41..118	CDD:214653	13/78 (17%)
		IG_like	145..218	CDD:214653	18/84 (21%)
		Ig	147..219	CDD:299845	18/83 (22%)
		I-set	224..323	CDD:254352	25/99 (25%)
		IGc2	236..314	CDD:197706	20/78 (26%)
		FN3	339..431	CDD:238020	22/99 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900