DRSC/TRiP Functional Genomics Resources

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Protein Alignment fipi and Lac

DIOPT Version :9

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:309 Identity:73/309 - (23%)
Similarity:125/309 - (40%) Gaps:40/309 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 AVAWANHHESLSLSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHKGRIHIEQTST 79
            :|.:|..:..|.|......|...|..:|:::    |.:..|.:.                ..:||
  Fly    51 SVQYAKEYNVLFLKTDSDPVFLSTGSTLVIK----DSRFSLRYD----------------PNSST 95

  Fly    80 EQLKIVFAHIALADKGNWSCEAADGSLHSKSFD--LIVYQKITFTENATVMTV-KEGEKATILCE 141
            .:|:|  ..|...|.|.::|:....::|..|.:  |.|.:....::|:|...| .||.:..:.|.
  Fly    96 YKLQI--KDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECY 158

  Fly   142 VKGEPQPNVTWHFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQER 206
            ..|.|.|.:||......|.  ..|.:.:  :.:.|.|..|.:.|.|.|.|.|   ::..|....|
  Fly   159 ASGYPTPTITWRRENNAIL--PTDSATY--VGNTLRIKSVKKEDRGTYYCVA---DNGVSKGDRR 216

  Fly   207 TVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQ--- 268
            .:.:::|..|:.: .|...|..| :.....|.|...|.||....|.:...:| :||:.|:|.   
  Fly   217 NINVEVEFAPVIT-VPRPRLGQA-LQYDMDLECHIEAYPPPAIVWTKDDIQL-ANNQHYSISHFA 278

  Fly   269 -SDSYW-SSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSP 315
             :|.|. |:|.:..:....:.:|.|:|.|..|..|....|.:...|..|
  Fly   279 TADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCP 327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653 16/83 (19%)
I-set 128..202 CDD:254352 19/74 (26%)
Ig 133..>193 CDD:299845 16/59 (27%)
IG_like 228..307 CDD:214653 22/83 (27%)
Ig 235..305 CDD:143165 21/74 (28%)
FN3 312..415 CDD:238020 2/4 (50%)
LacNP_523713.2 IG_like 36..131 CDD:214653 20/101 (20%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 73/309 (24%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 9/48 (19%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 4/9 (44%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 21/80 (26%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 24/93 (26%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442821
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.840

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