DRSC/TRiP Functional Genomics Resources

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Protein Alignment fipi and DIP-eta

DIOPT Version :10

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_608946.3 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster


Alignment Length:264 Identity:72/264 - (27%)
Similarity:118/264 - (44%) Gaps:35/264 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 EHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSKS--FDLIVYQKITFTENATVMT 129
            |||       |.|.::|    .|..:|||.:.|:.....:.|:.  .|::|...|.....:|.|.
  Fly   104 EHK-------TWTMRIK----DIKESDKGWYMCQINTDPMKSQMG
YLDVVVPPDILDYPTSTDMV 157

  Fly   130 VKEGEKATILCEVKGEPQPNVTW-HFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRA 193
            |:||...|:.|...|.|:|.:|| ..:|.||.. |..:....|....|:|..|.::..|.|.|.|
  Fly   158 VREGSNVTLKCAATGSPEPTITWRRESGVPIEL-ATGEEVMSIEGTDLVIPNVRRHHMGAYLCIA 221

  Fly   194 YQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGT----ATLMCEALAEPPANFTWYRK 254
              .|.:...:.:|..|  :.|.|     |.::::...|...    .||.||:.|.|.:...|.|:
  Fly   222 --SNGVPPSVSKRITL--VV
HFP-----PMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRE 277

  Fly   255 HNKLHSNNRLYT---IQSDSYWSSLTIHV--LNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPS 314
            ..::......|:   .:...|.:|:.:|:  |..:.|.:|||.|:|.||..:.|.:|.:  .||:
  Fly   278 RGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLY
R--IPPN 340

  Fly   315 PANF 318
            ..|:
  Fly   341 AVNY 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653 13/49 (27%)
IgI_Twitchin_like 120..208 CDD:409541 26/88 (30%)
Ig strand A 120..123 CDD:409541 0/2 (0%)
Ig strand A' 127..131 CDD:409541 1/3 (33%)
Ig strand B 134..141 CDD:409541 1/6 (17%)
Ig strand C 149..154 CDD:409541 2/5 (40%)
Ig strand C' 156..159 CDD:409541 1/2 (50%)
Ig strand D 165..170 CDD:409541 0/4 (0%)
Ig strand E 173..178 CDD:409541 1/4 (25%)
Ig strand F 187..195 CDD:409541 4/7 (57%)
Ig strand G 198..208 CDD:409541 1/9 (11%)
IG_like 228..307 CDD:214653 23/87 (26%)
Ig strand B 235..239 CDD:409353 2/3 (67%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)
FN3 312..415 CDD:238020 3/7 (43%)
DIP-etaNP_608946.3 IG_like 51..137 CDD:214653 12/43 (28%)
Ig strand B 60..64 CDD:409353
Ig strand C 73..77 CDD:409353
Ig strand E 108..112 CDD:409353 1/3 (33%)
Ig strand F 122..127 CDD:409353 1/4 (25%)
Ig strand G 134..137 CDD:409353 1/2 (50%)
IgI_1_MuSK 145..237 CDD:409562 28/96 (29%)
Ig strand A 145..148 CDD:409562 0/2 (0%)
Ig strand A' 153..158 CDD:409562 2/4 (50%)
Ig strand B 164..171 CDD:409562 2/6 (33%)
Ig strand C 177..182 CDD:409562 2/4 (50%)
Ig strand C' 184..186 CDD:409562 0/1 (0%)
Ig strand D 194..197 CDD:409562 0/2 (0%)
Ig strand E 202..208 CDD:409562 2/5 (40%)
Ig strand F 215..222 CDD:409562 4/8 (50%)
Ig strand G 229..237 CDD:409562 2/9 (22%)
IG_like 252..335 CDD:214653 22/82 (27%)
Ig strand B 258..262 CDD:409353 2/3 (67%)
Ig strand C 271..282 CDD:409353 2/10 (20%)
Ig strand E 301..306 CDD:409353 1/4 (25%)
Ig strand F 316..321 CDD:409353 3/4 (75%)
Ig strand G 329..332 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

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