DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and DIP-eta

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	72/264 - (27%)
Similarity:	118/264 - (44%)	Gaps:	35/264 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSKS--FDLIVYQKITFTENATVMT 129
            |||       |.|.::|    .|..:|||.:.|:.....:.|:.  .|::|...|.....:|.|.
  Fly   104 EHK-------TWTMRIK----DIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMV 157

  Fly   130 VKEGEKATILCEVKGEPQPNVTW-HFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRA 193
            |:||...|:.|...|.|:|.:|| ..:|.||.. |..:....|....|:|..|.::..|.|.|.|
  Fly   158 VREGSNVTLKCAATGSPEPTITWRRESGVPIEL-ATGEEVMSIEGTDLVIPNVRRHHMGAYLCIA 221

  Fly   194 YQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGT----ATLMCEALAEPPANFTWYRK 254
              .|.:...:.:|..|  :.|.|     |.::::...|...    .||.||:.|.|.:...|.|:
  Fly   222 --SNGVPPSVSKRITL--VVHFP-----PMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRE 277

  Fly   255 HNKLHSNNRLYT---IQSDSYWSSLTIHV--LNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPS 314
            ..::......|:   .:...|.:|:.:|:  |..:.|.:|||.|:|.||..:.|.:|.:  .||:
  Fly   278 RGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYR--IPPN 340

  Fly   315 PANF 318
            ..|:
  Fly   341 AVNY 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	13/49 (27%)
		I-set	128..202	CDD:254352	24/74 (32%)
		Ig	133..>193	CDD:299845	19/60 (32%)
		IG_like	228..307	CDD:214653	23/87 (26%)
		Ig	235..305	CDD:143165	22/74 (30%)
		FN3	312..415	CDD:238020	3/7 (43%)
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	12/47 (26%)
		IG_like	51..137	CDD:214653	12/43 (28%)
		IG_like	153..237	CDD:214653	27/88 (31%)
		Ig	161..224	CDD:299845	20/65 (31%)
		IG_like	252..335	CDD:214653	22/82 (27%)
		Ig	258..333	CDD:143165	22/74 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442853
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840