DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and dpr18

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	46/252 - (18%)
Similarity:	82/252 - (32%)	Gaps:	105/252 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SPDPKVELHWKSPKGEIIREHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSKSFD 112
            |.||::.:.::.|       :..|:.|..|.||            |.|.:.|:.   |.|...
  Fly   277 SGDPRIRVKFQYP-------NNWRLLINPTQTE------------DAGVYMCQV---STHPPR-- 317

  Fly   113 LIVYQKITFTENATVMT-----------------VKEGEKATILCEV-----KGEPQP------- 148
                   .||.|.||:.                 .|.|....:.|::     :.|.|.
  Fly   318 -------VFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQKERQTILKSTDS 375

  Fly   149 ----------------------NVTWH-FNGQPIS-------AGAADDSKFR-------ILADGL 176
                                  |.|.| |:||.:.       ..|.|:...:       .::|..
  Fly   376 ANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDEEPLQGMTNRRLSVSDVW 440

  Fly   177 LINKVT-----QNDTGEYACRAYQVNSIASDMQERT--VLMKIEHKPIWSKTPFVSL 226
            |.::::     .:|:|.|:|...::.::...:|..|  :...::|. |.|:|...||
  Fly   441 LTSRISIGDAKLSDSGNYSCSLGRLFTVIVQVQVLTGELPAAVQHN-IGSRTEIYSL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	14/66 (21%)
		I-set	128..202	CDD:254352	19/144 (13%)
		Ig	133..>193	CDD:299845	18/113 (16%)
		IG_like	228..307	CDD:214653
		Ig	235..305	CDD:143165
		FN3	312..415	CDD:238020
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	17/78 (22%)
		Ig	<258..326	CDD:299845	18/79 (23%)
		IGc2	<417..461	CDD:197706	7/43 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900