DRSC/TRiP Functional Genomics Resources

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Protein Alignment fipi and Negr1

DIOPT Version :9

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:344 Identity:77/344 - (22%)
Similarity:129/344 - (37%) Gaps:85/344 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 IVQCRSPDPKVELHWKSPKGEIIREHKG-----RIHIEQTSTEQLKIVFAHIALADKGNWSCE-- 100
            :..|......|:..|.:....::|  ||     |.::|..:::...:..:.|..|....||.:  
Mouse    22 LCSCLPAGQSVDFPWAAVDNMLVR--KGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPR 84

  Fly   101 AADGSLHSKSFDLIVYQKITFTENA-------------------TV------------MTVKEGE 134
            .:..:|:.:.:.|.: |.:..|::.                   ||            ||:.||.
Mouse    85 VSISTLNKRDYSLQI-QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGT 148

  Fly   135 KATILCEVKGEPQPNVTWHF---NGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQV 196
            ..|:.|...|:|:|.::|..   :.:|...|...|           |..:|::..|||.|.|  .
Mouse   149 NVTLTCLATGKPEPVISWRHISPSAKPFENGQYLD-----------IYGITRDQAGEYECSA--E 200

  Fly   197 NSIA-SDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTAT------LMCEALAEPPANFTWYRK 254
            |.:: .|:::..|::.           |........:||.|      :.||....||..|.||:.
Mouse   201 NDVSFPDVKKVRVIVN-----------FAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 254

  Fly   255 HNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGT----------IERTTRLEQG 309
            ..:|.:..:...||:.|..|.||:..:....|.||.|.|.|.|||          ||.||.....
Mouse   255 EKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSPVT 319

  Fly   310 EKPPSPANFQLRGFNSNTF 328
            ...||.|.:.:.|...:.|
Mouse   320 SPAPSTAQYGITGSACDLF 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653 14/78 (18%)
I-set 128..202 CDD:254352 21/77 (27%)
Ig 133..>193 CDD:299845 16/62 (26%)
IG_like 228..307 CDD:214653 30/94 (32%)
Ig 235..305 CDD:143165 27/85 (32%)
FN3 312..415 CDD:238020 5/17 (29%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 4/18 (22%)
Ig strand A' 40..46 CDD:409353 1/7 (14%)
IG_like 41..129 CDD:214653 13/90 (14%)
Ig strand B 48..56 CDD:409353 1/7 (14%)
CDR1 56..60 CDD:409353 1/3 (33%)
FR2 61..68 CDD:409353 0/6 (0%)
Ig strand C 61..67 CDD:409353 0/5 (0%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 5/35 (14%)
Ig strand D 84..91 CDD:409353 0/6 (0%)
Ig strand E 94..100 CDD:409353 1/6 (17%)
Ig strand F 107..115 CDD:409353 0/7 (0%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 0/8 (0%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig strand A' 139..144 CDD:409353 1/4 (25%)
IGc2 146..204 CDD:197706 19/70 (27%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 1/4 (25%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/16 (13%)
Ig strand F 193..200 CDD:409353 5/8 (63%)
Ig_3 219..295 CDD:404760 22/75 (29%)
putative Ig strand A 219..225 CDD:409353 0/5 (0%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 1/3 (33%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833602
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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