DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fipi and DIP-kappa

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster

Alignment Length:	367	Identity:	78/367 - (21%)
Similarity:	139/367 - (37%)	Gaps:	80/367 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VAWANHHESLSLSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHKG-RIHIEQTST 79
            |||........|| ..|:|:            |.:.::.|.:        .:|:. .:||::
  Fly   105 VAWVRVDTQTILS-IHHNVI------------SQNSRISLTY--------NDHRSWYLHIKE--- 145

  Fly    80 EQLKIVFAHIALADKGNWSCEAADGSLHSKSFDLIVYQKITFTENATV--MTVKEGEKATILCEV 142
                     :...|:|.:.|:.....:.|:...|.|.......|..|.  |.|:||:..:::|:.
  Fly   146 ---------VEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKA 201

  Fly   143 KGEPQPNVTW-HFNGQPISAGAADDSKFRILADG--LLINKVTQNDTGEYACRAYQVNSIASDMQ 204
            :|.|:|.|.| ..:|:.:..|....:    :.||  |.|.||::.....|.|.|  .|.:...:.
  Fly   202 RGYPEPYVMWRREDGEEMLIGGEHVN----VVDGELLHITKVSRLHMAAYLCVA--SNGVPPSIS 260

  Fly   205 ERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTW------------YRKHNK 257
            :| |.::::..|:.|...  .|:.||:.....|.|...|.|.:...|            .|..:|
  Fly   261 KR-VHLRVQFPPMLSIPN--QLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDK 322

  Fly   258 LHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRG 322
            ..:.:   |:...:.:..|.|..:..:.|..|||.|:|.||..:...:|::...|.:....::..
  Fly   323 YETTS---TVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMSL 384

  Fly   323 FN---------SNTFDVVLSAP--------RGPPDSPMGVNG 347
            .|         .|.||...:.|        .|...:..|.||
  Fly   385 LNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNG 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	11/82 (13%)
		I-set	128..202	CDD:254352	22/76 (29%)
		Ig	133..>193	CDD:299845	17/62 (27%)
		IG_like	228..307	CDD:214653	20/90 (22%)
		Ig	235..305	CDD:143165	18/81 (22%)
		FN3	312..415	CDD:238020	10/53 (19%)
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	17/99 (17%)
		IG_like	82..174	CDD:214653	18/101 (18%)
		IG_like	184..267	CDD:214653	24/89 (27%)
		IGc2	191..255	CDD:197706	20/69 (29%)
		IG_like	282..368	CDD:214653	20/88 (23%)
		Ig	288..367	CDD:143165	18/81 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442852
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840