DRSC/TRiP Functional Genomics Resources

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Protein Alignment fipi and Prtg

DIOPT Version :9

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001032740.2 Gene:Prtg / 315806 RGDID:1307157 Length:1193 Species:Rattus norvegicus


Alignment Length:535 Identity:110/535 - (20%)
Similarity:180/535 - (33%) Gaps:155/535 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 ILNLAALTAV--AWANHHESLSLSPAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHK 69
            :|.|..|.:|  .|:.........|.:.:|.|.....|..|.....| :::.|.. .|..:.|:|
  Rat    15 LLLLPPLGSVPGVWSFSELFFMKEPQDATVTRKDPVFLDCQAHGEGP-IKVTWLK-NGAKLSENK 77

  Fly    70 -------GRIHIEQTS---TEQLKIVFAHIALADKGNWSCEAAD--GSLHSKSFDLIVYQKITFT 122
                   |.::|.:..   .||          :|:|.:.|.|.:  |::.|:...|.:.....|.
  Rat    78 RIQVLSNGSLYISEAEGRRGEQ----------SDEGFYQCLAVNKYGAILSQKAHLTLSTISAFE 132

  Fly   123 ENATVMTVKEGEKATILCEVKGEPQPNVTWHFN--GQPISAGAADDSKFRILADGLL-INKVTQN 184
            .:.....|.||..|...|::...|...:||.||  ..|::.    ||:...|..|:| |......
  Rat   133 VHPVSTEVPEGGVARFSCKISSTPPAVITWEFNRTALPMTM----DSRVTALPSGVLQIYDAGPE 193

  Fly   185 DTGEYACRA-------------------------YQVNSIASDMQ-----ERTVLMKI----EHK 215
            |.|:|.|.|                         |....|||...     .:||:::.    ..|
  Rat   194 DAGKYRCVAATHAHKRKSMEASLTIVPANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYPK 258

  Fly   216 PI--WSKTPF--------------------VSLKYA--YI------------------------- 231
            ||  ||:...                    |.|::|  |:                         
  Rat   259 PIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPS 323

  Fly   232 ------------NGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTS 284
                        .|||..:|:|...|....:|.:...::|||.|:     ..|.|.|.|:.:...
  Rat   324 FVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRI-----KMYNSKLVINQIIPE 383

  Fly   285 AFDNYRCRARNDLGTI---ERTTRLEQGEKPPSPANFQLRGFNSNTFDVVLSAPRGPPDSPMGVN 346
            ....|:|.|.|..|::   .|.|.:...::|.:|.|......:|:   .:|.|...|..:...|.
  Rat   384 DDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSS---AILLAWERPLYNSDKVI 445

  Fly   347 GFRIEYMTEMEFKTDAGKWTNARRKDYAFEEG---ATFLLTNLEPD---TVYLVRAASRNLAGFS 405
            .:.:.||          |......::|....|   ..:::.:||||   |.|:|.......:..|
  Rat   446 AYSVHYM----------KAEGLNNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPMGASQMS 500

  Fly   406 DFTKVEKYKTLSLEP 420
            |.......:.:.|.|
  Rat   501 DHVTQNTLEDVPLRP 515

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653 20/93 (22%)
I-set 128..202 CDD:254352 25/101 (25%)
Ig 133..>193 CDD:299845 19/62 (31%)
IG_like 228..307 CDD:214653 24/120 (20%)
Ig 235..305 CDD:143165 19/72 (26%)
FN3 312..415 CDD:238020 22/108 (20%)
PrtgNP_001032740.2 Ig 32..124 CDD:416386 20/103 (19%)
Ig strand A 32..35 CDD:409353 0/2 (0%)
Ig strand A' 38..44 CDD:409353 1/5 (20%)
Ig strand B 48..58 CDD:409353 2/9 (22%)
Ig strand C 62..68 CDD:409353 1/5 (20%)
Ig strand C' 70..73 CDD:409353 1/2 (50%)
Ig strand D 78..83 CDD:409353 0/4 (0%)
Ig strand E 85..91 CDD:409353 2/5 (40%)
Ig strand F 103..110 CDD:409353 2/6 (33%)
Ig strand G 114..124 CDD:409353 2/9 (22%)
Ig 131..218 CDD:416386 23/90 (26%)
Ig strand B 146..150 CDD:409353 1/3 (33%)
Ig strand C 159..163 CDD:409353 1/3 (33%)
Ig strand E 183..187 CDD:409353 2/3 (67%)
Ig strand F 197..202 CDD:409353 2/4 (50%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 230..302 CDD:404760 14/71 (20%)
Ig strand B 247..251 CDD:409353 1/3 (33%)
Ig strand C 260..264 CDD:409353 1/3 (33%)
Ig strand E 282..286 CDD:409353 0/3 (0%)
Ig strand F 296..301 CDD:409353 1/4 (25%)
I-set 322..407 CDD:400151 21/89 (24%)
Ig strand C 352..357 CDD:409353 1/4 (25%)
Ig strand C' 359..362 CDD:409353 0/2 (0%)
Ig strand D 367..371 CDD:409353 1/8 (13%)
Ig strand E 373..378 CDD:409353 2/4 (50%)
Ig strand F 387..394 CDD:409353 3/6 (50%)
Ig strand G 398..407 CDD:409353 1/8 (13%)
FN3 414..507 CDD:238020 22/105 (21%)
FN3 512..605 CDD:238020 2/4 (50%)
fn3 619..694 CDD:394996
FN3 721..809 CDD:238020
FN3 816..906 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 974..1018
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1078..1193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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