DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and kirre

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	79/414 - (19%)
Similarity:	138/414 - (33%)	Gaps:	121/414 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 HHESLSLSPAEHSVVR-YTNESLIVQCRSPDPKVELH--------WKSPKG-EIIREHKGRIHIE 75
            ||.:.....|:::..| |.:..|:::.:.. |||.:.        .|.|:| |:|...:...:..
  Fly   261 HHNTTFTCQAQNTADRTYRSAKLLLEVKYA-PKVIVSVVGGALAGGKIPEGAEVILSCQADANPH 324

  Fly    76 QTS-----TEQL-------KIVF------AHIALADKGNWSCE---AADGSLHSKSFDLIVYQKI 119
            :.|     .::|       |::.      .|.|:.     .||   |...|..||..| |.:..:
  Fly   325 ELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIV-----KCEVVNAVGKSEQSKKLD-ISFGPV 383

  Fly   120 TFTENATVMTVKEGEKATILCEVKGEPQPNVTWHFNGQPISAGAADDSKFRILADGLLINKVTQN 184
             |.:....:....|...::.|:|.|.|:|.:.|.........|.|.:.|.          ||:..
  Fly   384 -FRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKL----------KVSSE 437

  Fly   185 DTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVS---LKYAYINGTATLMCEALAEPP 246
            ..|.|.|:|. ||.......|.|:.:|        :.|.::   :::..:.|...:.|.|.:.|.
  Fly   438 TAGRYFCKAV-VNGFPEIGAEATLYVK--------RAPIITSHKVQFGGVGGRVKIDCLAFSIPK 493

  Fly   247 ANFTWYRKHNKL----HSNNRLYTIQS----DSYWSSLTIHVLNTSAFDNYRCRARNDLG----- 298
            |....:....|:    .::..:|..:.    :...::|.|.....:.|..|.|...|..|
  Fly   494 AEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYGGDSLV 558

  Fly   299 -TIER-----------------------------TTRLEQGEKPPSPANFQLRGFNSNTFDVVLS 333
             |:.|                             ..|..:..|.|.||            ||:..
  Fly   559 ITLLREPGNIPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMPA------------DVIPE 611

  Fly   334 APRGPP-----DSPMGVNGFRIEY 352
            |.||..     .|.:....:.:||
  Fly   612 ASRGGDKLNELKSELRSKAYDVEY 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	23/112 (21%)
		I-set	128..202	CDD:254352	18/73 (25%)
		Ig	133..>193	CDD:299845	15/59 (25%)
		IG_like	228..307	CDD:214653	17/121 (14%)
		Ig	235..305	CDD:143165	15/112 (13%)
		FN3	312..415	CDD:238020	11/46 (24%)
kirre	NP_001245505.1	Ig	87..183	CDD:299845
		IG_like	88..182	CDD:214653
		C2-set_2	189..279	CDD:285423	4/17 (24%)
		Ig_2	307..379	CDD:290606	16/77 (21%)
		I-set	382..462	CDD:254352	21/91 (23%)
		IGc2	396..446	CDD:197706	15/59 (25%)
		Ig	466..561	CDD:299845	15/94 (16%)
		IG_like	478..561	CDD:214653	14/82 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900