DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fipi and Ntm

DIOPT Version :9

Sequence 1:NP_787975.1 Gene:fipi / 33676 FlyBaseID:FBgn0031627 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:310 Identity:75/310 - (24%)
Similarity:127/310 - (40%) Gaps:52/310 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LTAVAWANHHESLSLSPAEHSVVRYT-NESLIVQCRSPDPKVELHWKSPKGEIIREHKGRIHIEQ 76
            :|.|||.|           .|.:.|. |:...:     ||:|.|                  :..
Mouse    63 VTRVAWLN-----------RSTILYAGNDKWCL-----DPRVVL------------------LSN 93

  Fly    77 TSTEQLKIVFAHIALADKGNWSCEA-ADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILC 140
            |.| |..|...::.:.|:|.::|.. .|....:....|||.......|.::.:::.||...::.|
Mouse    94 TQT-QYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTC 157

  Fly   141 EVKGEPQPNVTW-HFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQ 204
            ...|.|:|.||| |.:  |.:.|...:.::      |.|..:|:..:|||.|.|  .|.:|:.:.
Mouse   158 IATGRPEPTVTWRHIS--PKAVGFVSEDEY------LEIQGITREQSGEYECSA--SNDVAAPVV 212

  Fly   205 ERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALAEPPANFTWYRKHNKLHSNNRLYTIQS 269
            .| |.:.:.:.|..|:.....:.   :....||.|||.|.|.|.|.|::...:|....:...:::
Mouse   213 RR-VKVTVNYPPYISEAKGTGVP---VGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVEN 273

  Fly   270 DSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQ 319
            ..:.|.||...::...:.||.|.|.|.||....:..|.:..:|.|....|
Mouse   274 RPFLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQ 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fipiNP_787975.1 IG_like 33..115 CDD:214653 16/83 (19%)
I-set 128..202 CDD:254352 22/74 (30%)
Ig 133..>193 CDD:299845 18/60 (30%)
IG_like 228..307 CDD:214653 21/78 (27%)
Ig 235..305 CDD:143165 21/69 (30%)
FN3 312..415 CDD:238020 3/8 (38%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 21/103 (20%)
Ig strand A' 44..49 CDD:409353
Ig strand B 51..59 CDD:409353
CDR1 59..63 CDD:409353 75/310 (24%)
FR2 64..70 CDD:409353 4/5 (80%)
Ig strand C 64..70 CDD:409353 4/5 (80%)
CDR2 71..83 CDD:409353 3/11 (27%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/57 (19%)
Ig strand D 87..94 CDD:409353 2/24 (8%)
Ig strand E 97..103 CDD:409353 2/5 (40%)
Ig strand F 110..118 CDD:409353 2/7 (29%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 1/8 (13%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 21/78 (27%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 1/8 (13%)
Ig strand F 197..205 CDD:409353 5/9 (56%)
Ig_3 222..299 CDD:404760 20/79 (25%)
putative Ig strand A 223..229 CDD:409353 2/5 (40%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 1/3 (33%)
Ig strand E 278..282 CDD:409353 2/3 (67%)
Ig strand F 292..297 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833606
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

Return to query results.
Submit another query.