DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and zig-6

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_508882.3	Gene:	zig-6 / 192089	WormBaseID:	WBGene00006983	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	59/279 - (21%)
Similarity:	110/279 - (39%)	Gaps:	56/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RLIGFILNLAALTAVAWANHHESLSLSPAEHSVVRYTNESLIVQCR-----SPDPKVELHWKSPK 61
            :|...:|.|..|.:.::|....::|:||..:.|.:.....:.:.|.     |...|..:.||...
Worm     3 KLCLLLLPLVFLVSYSFAEEEITISISPNANPVQKPIGHQISLVCSIKKTDSNGEKPGMIWKKHG 67

  Fly    62 GEIIREHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGS-LHSKSFDLIVYQKITFTEN- 124
            |   .:..|.:.:::.....|.::..:.::.|.|.:.|:|..|| ::....|:||::.|.|.:.
Worm    68 G---LDRTGNVEVKKLDDYTLGLIIRNSSVEDSGVYYCQAQVGSKVYMNKMDVIVFEDIVFRDKQ 129

  Fly   125 -------ATVMTVKEGEKATILCEVKGEPQPNVT-WHFNGQPISAGAADDSKFRILADGLLI--- 178
                   ||.       ...|.|||..:....:| |..:|:.|..|    .|.:..:.|.::
Worm   130 LHFGQVLATA-------SVNISCEVSAKKDSVITYWTRHGKQILEG----GKHKFYSRGSILEIQ 183

  Fly   179 NKVTQNDTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTATLMCEALA 243
            |...:.|.|:|.|..:.|:|.:|:.:..|:....|..              |:  ....||.:..
Worm   184 NYQPEQDAGQYTCEVFHVSSGSSNTKTVTLGTTGEKN--------------YV--ACQQMCNSFC 232

  Fly   244 EPPANFTWYRKHNKLHSNN 262
            ..        .|||:.:||
Worm   233 TD--------VHNKVFTNN 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	16/87 (18%)
		I-set	128..202	CDD:254352	18/77 (23%)
		Ig	133..>193	CDD:299845	16/63 (25%)
		IG_like	228..307	CDD:214653	8/35 (23%)
		Ig	235..305	CDD:143165	7/28 (25%)
		FN3	312..415	CDD:238020
zig-6	NP_508882.3	IG_like	34..119	CDD:214653	16/87 (18%)
		Ig	45..109	CDD:299845	13/66 (20%)
		IG_like	135..213	CDD:214653	21/88 (24%)
		ig	140..213	CDD:278476	19/76 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910