DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and zig-2

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	57/242 - (23%)
Similarity:	86/242 - (35%)	Gaps:	56/242 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SCEAADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKGEPQPNVTWHFNGQPISAG 162
            :.|:.|.....::.|.....|.|.|.|.:.:|.  |||..:.|...|.|.|::.|..||..|...
Worm    14 AAESVDHQKPIRALDSQPLLKFTRTPNDSNVTF--GEKFVLSCGANGAPLPSIYWELNGMRIQGE 76

  Fly   163 AADDSKFRILADGLLINK------------VTQNDTGEYACRAYQVNSIASDMQERTVLMKIEH- 214
            ...:....||.||..::.            .|..::|.|.|       |..:     .|.|:||
Worm    77 ETSNVYENILNDGKQVSNAAMVSSHYRIPCATARNSGAYKC-------IIDN-----GLTKLEHV 129

  Fly   215 KPIW---SKT---------PFVSL----KYAYINGTATLMCEALAEPPANFTWYRKHNKLHSNNR 263
            ..::   :||         ||:|:    :....|....|.|.  :|....::|       |...:
Worm   130 AKVFVGGNKTNCALNDNGAPFISMTVDFRLEISNNAVALSCR--SETATEWSW-------HKGEQ 185

  Fly   264 LYTIQSDSYW----SSLTIHVLNTSAFDNYRCRARNDLGTIERTTRL 306
            |.|...:.|.    ..|.|..::.|....|.|.|||..|.....|.|
Worm   186 LLTNDGERYQMFPSGDLIIRNISWSDMGEYNCTARNHFGETTAITFL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	3/16 (19%)
		I-set	128..202	CDD:254352	21/85 (25%)
		Ig	133..>193	CDD:299845	19/71 (27%)
		IG_like	228..307	CDD:214653	20/83 (24%)
		Ig	235..305	CDD:143165	17/73 (23%)
		FN3	312..415	CDD:238020
zig-2	NP_510069.1	I-set	34..134	CDD:254352	29/113 (26%)
		Ig	34..121	CDD:299845	25/95 (26%)
		Ig	<179..232	CDD:299845	15/59 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900