DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and rig-3

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	433	Identity:	100/433 - (23%)
Similarity:	170/433 - (39%)	Gaps:	86/433 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ESLIVQC--RSPDP--KVELHWKSPKG------------EIIREHKGRIHIEQTSTEQLKIVFAH 88
            :.|:|.|  .|.:.  |.:|.||...|            .:|...||..| .:||     :.|:.
Worm    55 KKLMVSCVFESDEQIHKSDLLWKQANGNNIDGESNPSLFSVILNEKGSKH-RKTS-----LHFSS 113

  Fly    89 IALADKGNWSC--EAADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKG----EPQ 147
            :...|.|.::|  ..|.|....|:..|:|...|.:.:..||.....||..||.|.|||    ||.
Worm   114 VHTRDTGLYTCTGRTAGGENFEKTIKLVVLPAIEWNDKDTVKGALLGEPITIDCGVKGPSGKEPM 178

  Fly   148 PNVTWHFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQERT----- 207
            ..:| :.||:|:     |:..:.|..:...|:.:.:    |:|  ...|:.|..:|.:.|
Worm   179 IQMT-NGNGEPL-----DEEIWTIAGNEATIDSLKK----EHA--ELTVSCITIEMHQETSKEEF 231

  Fly   208 --VLMKIEHKPIWSKTPF---VSLKYAYING---TATLMCEAL-AEPPA-NFTWYRKHNKLHSNN 262
              |..|..:..:::...|   .|::|..|:.   .|.:.|... :.||. ::|:|....::..::
Worm   232 PVVDRKDVNIEVYTLPEFETEESVQYTVIDNHVRDAIIYCNVTHSFPPVRHYTFYHGDEEIKMSD 296

  Fly   263 R--LYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRGFNS 325
            :  ::.....|..:.|.||.:|.:....|:|.|.|.......|..|.:...|..|....:.....
Worm   297 KFNIFVNVGVSQGAHLKIHNVNENDLGTYKCEANNIKAKSYHTIHLREANAPAEPKVTLIEDKRH 361

  Fly   326 NTFDVVLSAPRGPPDSPMGVNGFRIEYMTEMEFK------TDAGKWTNARRKDYAFEEGATFLLT 384
            :....|.|..| .||.|          ||.:|.:      .:|...::....|..::..:.|:..
Worm   362 SIIWKVESIDR-DPDLP----------MTAVEIRHLRAGTAEASGVSDEDISDAYWKSHSIFMQR 415

  Fly   385 NLEPDTVYLV-----------RAASRNLAGFSDFTKVEKYKTL 416
            |::.|.:|.:           |....|.|||.| :.|.:.|||
Worm   416 NIKDDGIYEINGLRHGHEYVWRFRQINEAGFGD-SVVLRAKTL 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	23/92 (25%)
		I-set	128..202	CDD:254352	21/77 (27%)
		Ig	133..>193	CDD:299845	19/63 (30%)
		IG_like	228..307	CDD:214653	18/85 (21%)
		Ig	235..305	CDD:143165	16/73 (22%)
		FN3	312..415	CDD:238020	24/119 (20%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653	23/92 (25%)
rig-3	NP_509155.1	Ig	267..341	CDD:319273	16/73 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810