DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and zig-8

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	45/238 - (18%)
Similarity:	84/238 - (35%)	Gaps:	65/238 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILNLAALTAVAWANHHESLSLSPAEHSVVRYTNESLI---------VQCR-SPDPKVELHW---- 57
            ::..:.|.|.......|.::....|.|.|...:::::         :.|. .||.:.|:.|
Worm     9 VILFSFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENPAYLHCSVPPDAEHEIAWTRVS 73

  Fly    58 -------------KSPKGEIIREHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSK 109
                         :.|:.::.::......:.....||          .|.|.:.||..|  .|:.
Worm    74 DGALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQ----------QDSGCYLCEIND--KHNT 126

  Fly   110 SFDLIVYQKI---------TFTENAT-VMTVKEGEKATILCEV----KGEPQPNVTWHFNGQPIS 160
            .:  .||.|:         :..:.:| :|....|::..:.|.|    |.|...:|.|..:|..|:
Worm   127 VY--AVYLKVLEPPLPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTIN 189

  Fly   161 AGAADDSKF--------RILADGLLINKVTQNDTGEYACRAYQ 195
            ..  |..|:        .::.:.:.|.|.|..|.|.|||...|
Worm   190 FN--DTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHSQ 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	16/108 (15%)
		I-set	128..202	CDD:254352	21/80 (26%)
		Ig	133..>193	CDD:299845	19/71 (27%)
		IG_like	228..307	CDD:214653
		Ig	235..305	CDD:143165
		FN3	312..415	CDD:238020
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	16/92 (17%)
		Ig	55..129	CDD:143165	14/87 (16%)
		ig	158..229	CDD:278476	19/72 (26%)
		IG_like	158..227	CDD:214653	18/70 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900