DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and iglon5

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	75/300 - (25%)
Similarity:	133/300 - (44%)	Gaps:	35/300 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PAEHSVVRYTNESLIVQCRSPDPKVELHWKSPKGEIIREHK------GRIHIEQTSTEQLKIVFA 87
            ||::..|. ..::..:.|...|....:.|.: :..|:...|      .|:.:...:..:..||..
Frog    32 PADNYTVS-QGDNATLSCLIDDKVTRVAWLN-RSNILYAGKDKWSIDSRVQLLTNTKSEYSIVIT 94

  Fly    88 HIALADKGNWSCE-AADGSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKGEPQPNVT 151
            |:.:||:|.::|. ..:...|:....|||.........::.:||.||....:.|...|:|:|.:|
Frog    95 HVDVADEGLYTCSFQTEDKPHTSQVYLIVQVPAKIVNISSSVTVNEGSNVNLQCLAVGKPEPTIT 159

  Fly   152 WHFNGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQE-RTVLMKIEHK 215
            |    |.:|.|.:.:.:.      |.|.::.:...|:|.|    |.|....:.: :.|.:.:.:.
Frog   160 W----QQLSEGFSSEGEL------LEITEINRQQAGDYEC----VTSNGVSVPDTKKVQITVNYP 210

  Fly   216 PIWSKTPFVSLKYAY--INGTATLMCEALAEPPANFTWYR-KHNKLHSNNRLYTIQSDSYWSSLT 277
            |.     ...:|.|.  :...|||.|:|:|.|||.|.||: :..:|.|.....:|:::|.||.:.
Frog   211 PY-----ITDVKNAQSPVGRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIKTESSWSVIV 270

  Fly   278 IHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPAN 317
            ...:.:..:.||.|.|.|.||:...:.||   .||..|.|
Frog   271 FSNVTSRHYGNYTCLASNKLGSFNSSLRL---LKPGDPLN 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	16/88 (18%)
		I-set	128..202	CDD:254352	20/73 (27%)
		Ig	133..>193	CDD:299845	15/59 (25%)
		IG_like	228..307	CDD:214653	27/81 (33%)
		Ig	235..305	CDD:143165	25/70 (36%)
		FN3	312..415	CDD:238020	2/5 (40%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	18/92 (20%)
		IG_like	35..123	CDD:214653	16/89 (18%)
		Ig	126..207	CDD:299845	21/94 (22%)
		I-set	128..207	CDD:254352	21/92 (23%)
		I-set	210..299	CDD:254352	28/93 (30%)
		Ig	227..298	CDD:143165	25/70 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11647
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910