DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and chl1b

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_017212175.2	Gene:	chl1b / 100318566	ZFINID:	ZDB-GENE-091105-1	Length:	1294	Species:	Danio rerio

Alignment Length:	374	Identity:	86/374 - (22%)
Similarity:	139/374 - (37%)	Gaps:	91/374 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ESLIVQCRS---PDPKVELHW------KSPKGEIIREHKGRIHIEQTSTEQLKIVFAHIALADKG 95
            |.|.::|.:   |.||||  |      |.|:..::..|...:.:|..:.|            |:|
Zfish   277 EDLQLECIAEGFPTPKVE--WVKIGFNKLPERVVVESHGKLLTVEMVNEE------------DEG 327

  Fly    96 NWSCEAADGSLHSK---SFDLIVYQKITFTENATVMTVKEGEKATILCEVKGEPQPNVTWHFNGQ 157
            .:.|.|.:.  |.:   .|.:.|.:...|........|..|....|.|.|||.|||.|.|..||:
Zfish   328 KYMCRAKNP--HGEVVHHFHVTVEEPPEFEIEPQSQLVTIGADVLIKCVVKGNPQPTVGWRVNGR 390

  Fly   158 PISAGAADDSKFRILADGLL-INKVTQNDTGEYACRAYQVNSIASDMQERTV-LMKIEHKPIWSK 220
            |::  ....|..:||.||.: |:.....::..|.|.|  .|...:.:....: :|.|:
Zfish   391 PLN--EVPTSNRKILKDGTISIHNANPENSAVYQCEA--TNKHGTILANANIMIMNIQ------- 444

  Fly   221 TPFV----SLKYAYINGTATLM-CEALAEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHV 280
             |.:    :|:|..:.|.:.:| |:..:.|.::.||.:..:........:|:..:   .||.||.
Zfish   445 -PLILTENNLQYMAVEGKSVVMHCKVFSSPASSITWSKADSANAVEGERFTVHQN---GSLEIHN 505

  Fly   281 LNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRGFNSNTFDVVLSAPRGPPDSPMGV 345
            :.......|.|.|:|..|.:.....||  .|.|:              .:|     .||.....:
Zfish   506 VMKEDMGEYSCFAQNTEGKVAIAATLE--VKDPT--------------RIV-----DPPRDLRVL 549

  Fly   346 NGFRIEYMTEMEFKTDAGK-----WTNARRKD-----------YAFEEG 378
            .|..|::..:.||....|.     |    .||           |..|:|
Zfish   550 AGTTIQFSCQPEFDPSFGDDFEVLW----EKDGIALNGSEDGRYILEDG 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	20/86 (23%)
		I-set	128..202	CDD:254352	25/74 (34%)
		Ig	133..>193	CDD:299845	22/60 (37%)
		IG_like	228..307	CDD:214653	17/79 (22%)
		Ig	235..305	CDD:143165	15/70 (21%)
		FN3	312..415	CDD:238020	15/83 (18%)
chl1b	XP_017212175.2	Ig	61..135	CDD:325142
		Ig	138..231	CDD:325142
		Ig	279..348	CDD:325142	19/84 (23%)
		Ig	366..438	CDD:325142	24/75 (32%)
		IG	454..533	CDD:214652	19/83 (23%)
		I-set	538..628	CDD:333254	14/66 (21%)
		FN3	632..722	CDD:238020
		FN3	734..815	CDD:238020
		FN3	832..931	CDD:238020
		fn3	942..1022	CDD:306538
		FN3	1070..1142	CDD:214495
		Bravo_FIGEY	1196..1279	CDD:316405
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100