DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fipi and vsig10

DIOPT Version :9

Sequence 1:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001093564.2	Gene:	vsig10 / 100005564	ZFINID:	ZDB-GENE-030131-7476	Length:	529	Species:	Danio rerio

Alignment Length:	321	Identity:	71/321 - (22%)
Similarity:	118/321 - (36%)	Gaps:	90/321 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SLSLSPAEHSVVRYTNESLIV--------QCRS-PDPKVELHW-------KSPKGEIIREHKGRI 72
            ||.:|||..    ..|.:|.|        .|.| .:|...|.|       .:|:.|.
Zfish   124 SLDISPATF----LNNGTLFVHKGSNVNFSCSSESNPSQNLTWTVDNLASDNPEREF-------- 176

  Fly    73 HIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLH----SKSFDLIVYQKITFTENATVMTVKEG 133
                .|...|.....:|...|:|.::| .:..:|.    :|:.:|:||..   .|.....:.:.|
Zfish   177 ----GSKSPLAFSITNIQPLDQGTYTC-TSQNTLSRRTANKTQELLVYYA---PERHPECSWELG 233

  Fly   134 EKAT---ILCE-VKGEPQPNVTWHFNGQPISAGAADDSKFRILAD------GLLINKVTQNDTGE 188
            :|.:   .:|. ..|.|.|.:||    |.:. |||:.....:...      .:.:|:...:|..:
Zfish   234 DKPSDVLFICSWFGGYPVPTLTW----QEVE-GAAEGPTINLTTSQQTEELNVSVNRSILHDGDK 293

  Fly   189 YACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAY---------INGT-ATLMC-EAL 242
            ..|..:.|..:                   .|:...:||..|         :.|| .|:.| |..
Zfish   294 VKCTGHHVTGV-------------------EKSCSFTLKIPYPTGQPLATALEGTNITISCTETS 339

  Fly   243 AEPPANFTWYRKHNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDN--YRCRARNDLGTIE 301
            :.|||...| :|::.|..|...|.:|.:.  .:||:.::|.:..|.  |.|.:.|.||..|
Zfish   340 SLPPAKTVW-KKNDDLIENTSKYIVQENR--PALTLTIVNVTKADEGVYYCYSENPLGARE 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fipi	NP_787975.1	IG_like	33..115	CDD:214653	19/101 (19%)
		I-set	128..202	CDD:254352	16/83 (19%)
		Ig	133..>193	CDD:299845	15/69 (22%)
		IG_like	228..307	CDD:214653	25/87 (29%)
		Ig	235..305	CDD:143165	22/70 (31%)
		FN3	312..415	CDD:238020
vsig10	NP_001093564.2	IG_like	28..116	CDD:214653
		Ig	32..104	CDD:299845
		IG_like	140..204	CDD:214653	14/76 (18%)
		IGc2	143..203	CDD:197706	13/72 (18%)
		IG_like	324..404	CDD:214653	24/77 (31%)
		Ig	328..404	CDD:299845	24/73 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100