DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and otud4

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001072598.1	Gene:	otud4 / 780053	XenbaseID:	XB-GENE-5900161	Length:	1051	Species:	Xenopus tropicalis

Alignment Length:	460	Identity:	105/460 - (22%)
Similarity:	184/460 - (40%)	Gaps:	106/460 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDE 84
            :|.:|....|:||.:..|.|.|||.|||||..:|..|.::|..|:.|:......:...:.|.|::
Frog    19 MDSYLRSEGLYRKKIAKDGSCLFRAVAEQVMHSQSEHLKIRKSCINYLRKNRGQYEALIEGSFED 83

  Fly    85 YLWHLGKTKTAGTILELGAMCHLYRRNVIIY-EPFDMGRMVTYNKDYKEILRIFMNSMGHFETVL 148
            ||..|...:.....:|:.|:..:::::.||| ||......||.|...::|:..|.|. .|::.:.
Frog    84 YLKSLENPQEWVGQVEISALSLMFKKDFIIYQEPNVPPACVTENGFSEKIMLCFSNG-NHYDIIY 147

  Fly   149 TMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTF------------KMGTEYEFDSR 201
            .:...:.||:|||:.:::||:   ::..|::. ::|:..||.            ..|:|.|..|:
Frog   148 PIGFAESAAMCQSIIYELLYE---KVMGVNVG-KYMVEQDTCGPNATGEVYCSDGSGSEGEDVSK 208

  Fly   202 GRAIRLLCRNGRSFKLDRPESTICLLENSQMCPFHNRRLAMGGQFADFSCMRILLEENNIPFSYL 266
            .........||  ||..:.:.          ||...:.                 |...:|   .
Frog   209 NIKTNFADMNG--FKPHKDDK----------CPQKKKE-----------------EPTMLP---S 241

  Fly   267 VAKSMDPCRYRNVELTSAIEARR--EAYEFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSI 329
            |.:|:...:|||||....::.:|  :..:|.|..| ..:.||.||||:::...:  ....:||.:
Frog   242 VLRSLHTTQYRNVEYEVWLKTQRDQQKLDFSIAAG-MQYSVGDKCQVRVEPGGK--FYNAHIQEV 303

  Fly   330 DKKKSVCKVFIEEQGKLVDVPSDNLHPLPPD--EFKAWDFARKRPQRLH---------------- 376
            ..:.....||:||.|:...|...:|.|:|..  ..:.|:....:.|:..
Frog   304 GTETGPVIVFVEELGEKHAVQLKHLKPIPQTIISTEGWNTVAGKKQKKALPSGTNAQTEKDYRGQ 368

  Fly   377 ----------------------------NSQMGRQSVQGDQQGFVPDPMPGTAPSMPPPPVADPR 413
                                        :||:..|:.|.:.:|     ...|.|.:|...|...|
Frog   369 KGFGKPVKQQAAQPLRQQQAAGNKQYGLSSQLSDQAPQSENKG-----RSKTPPKVPGRKVERER 428

  Fly   414 PVNVT 418
            ..|||
Frog   429 SENVT 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	23/78 (29%)
otud4	NP_001072598.1	OTU	36..>115	CDD:303090	24/78 (31%)
otud4	NP_001072598.1	TUDOR	282..330	CDD:119391	14/49 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10406
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9555
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1801
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910