DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and Otud1

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_081991.1	Gene:	Otud1 / 71198	MGIID:	1918448	Length:	454	Species:	Mus musculus

Alignment Length:	166	Identity:	37/166 - (22%)
Similarity:	67/166 - (40%)	Gaps:	28/166 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDEY 85
            |::|.:|..:|.|::.|.:.|:|.|::.||..|.||.|:|.:.|.|:......|...:.||..|:
Mouse   274 DKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEF 338

  Fly    86 LWHLGKTKTAGTILELGAMCHLYRRNVII-----YEPFDMGRMVTY---NKDYKEILRIFMNSMG 142
            :....:........||.||..:...|:.:     .|...:..|:.|   ....:..:.:...|.|
Mouse   339 IIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNG 403

  Fly   143 HFETVLTMQDVDMAAVCQSVSFKMLYKHLFRLPDVD 178
            |::.|                    :.|.:..|:.|
Mouse   404 HYDAV--------------------FDHSYPNPEYD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	22/83 (27%)
Otud1	NP_081991.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..64
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..257
		Cys-loop. /evidence=ECO:0000250	287..293		1/5 (20%)
		OTU	288..405	CDD:280496	27/116 (23%)
		His-loop. /evidence=ECO:0000250	342..352		0/9 (0%)
		Variable-loop. /evidence=ECO:0000250	399..404		1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700