DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and otud5a

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001068578.1	Gene:	otud5a / 555459	ZFINID:	ZDB-GENE-030616-61	Length:	560	Species:	Danio rerio

Alignment Length:	183	Identity:	49/183 - (26%)
Similarity:	80/183 - (43%)	Gaps:	14/183 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDEYLWHL 89
            |::....|.|..|.:.|||.||:|||..|.:|..||..|:.|:......|..:|:.||..|:...
Zfish   207 EKKGFVIKKMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRK 271

  Fly    90 GKTKTAGTILELGAMCHLYRRNVIIY----EPFDMGRMVTYNKDYKEILRIFMNSMGHFETVLTM 150
            .|....|..:|:.||..:|.|.|.:|    ||.:....:..|.|  |.:|:..:...|:.:|:..
Zfish   272 RKNNCHGNHIEMQAMAEMYNRPVEVYQSGTEPINTFHGIHQNND--EPIRVSYHRNIHYNSVVNP 334

  Fly   151 QDVDMAAVCQSVSFK------MLYKHLFRLPDVDLAVEWMLYPDTFKMGTEYE 197
            ....:.......:||      .|.|:..:..:.....:.||  :..|..|::|
Zfish   335 NKATIGVGLGLPAFKPGFADQSLMKNAIKTSEESWIEQQML--EDKKRATDWE 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	28/78 (36%)
otud5a	NP_001068578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..105
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..190
		Cys-loop. /evidence=ECO:0000250	216..222		2/5 (40%)
		OTU	219..328	CDD:303090	35/110 (32%)
		Variable-loop. /evidence=ECO:0000250	271..281		2/9 (22%)
		His-loop. /evidence=ECO:0000250	322..327		0/4 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	411..496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910