DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and OTUD6B

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_057107.4	Gene:	OTUD6B / 51633	HGNCID:	24281	Length:	293	Species:	Homo sapiens

Alignment Length:	175	Identity:	39/175 - (22%)
Similarity:	78/175 - (44%)	Gaps:	31/175 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRLASTEVRK---AR----DPIDRFLERRQLFRKHMLGDASSLFRVVAEQV--YDTQMLHYEVRM 61
            :|:|..|:..   ||    :.:.:.|..|||..|.:..|...:::.:.:|:  .|..:....:|.
Human   117 ERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRS 181

  Fly    62 ECVRYMFTKWKTFRRFV----SGD------FDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYE 116
            :...||.:..:.|..|:    :||      |.:|...:..|...|..|||.|:.|:.:..:.|.:
Human   182 QTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQ 246

  Fly   117 ----PFDMGRMVTYNKDYKEILRIFMN---SMG-HFETVLTMQDV 153
                |..:|.  .|:|  |.::.::|.   .:| |:.:|..:.::
Human   247 ADSPPIIVGE--EYSK--KPLILVYMRHAYGLGEHYNSVTRLVNI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	19/90 (21%)
OTUD6B	NP_057107.4	COG5539	18..280	CDD:227826	38/166 (23%)
		Cys-loop. /evidence=ECO:0000250	152..158		1/5 (20%)
		OTU	153..278	CDD:280496	27/128 (21%)
		Variable-loop. /evidence=ECO:0000250	219..229		2/9 (22%)
		His-loop. /evidence=ECO:0000250	267..277		2/9 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840