DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and Otud6a

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001156663.1	Gene:	Otud6a / 408193	MGIID:	3644685	Length:	290	Species:	Mus musculus

Alignment Length:	126	Identity:	25/126 - (19%)
Similarity:	51/126 - (40%)	Gaps:	22/126 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRLASTEVRKARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRY---- 66
            ::||:.. |:..:.:...|..:.|..|.:..|...::|.:.:|      |.:.|.:|.:||
Mouse   120 EQLAANR-REEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQ------LVFSVTIESLRYRTAY 177

  Fly    67 -----------MFTKWKTFRRFVSGDFDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYE 116
                       .||:.:....:...||..|...:....:.|..|||.|:.|:.:..:.:.:
Mouse   178 YMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHNASWGGQLELRALSHVLQTPIEVVQ 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	19/93 (20%)
Otud6a	NP_001156663.1	COG5539	5..272	CDD:227826	25/126 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..117
		Cys-loop. /evidence=ECO:0000250	147..153		1/5 (20%)
		OTU	148..270	CDD:280496	19/97 (20%)
		Variable-loop. /evidence=ECO:0000250	211..221		1/9 (11%)
		His-loop. /evidence=ECO:0000250	259..269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840