DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and otud6b

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_956519.1	Gene:	otud6b / 393194	ZFINID:	ZDB-GENE-040426-974	Length:	293	Species:	Danio rerio

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	74/180 - (41%)	Gaps:	43/180 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RLASTEVR-----------KARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQML--HYE 58
            |:|..||.           |.|:.    |..|.|..|.:..|...::|.|..|:.:..:.  ..|
Zfish   118 RIAEAEVENLSGSRHQEGLKLREK----LVERHLQIKEISSDGHCMYRAVEHQLTERGLALGLKE 178

  Fly    59 VRMECVRYMFTKWKTFRRFV----SGD------FDEYLWHLGKTKTAGTILELGAMCHLYRRNVI 113
            :|.:..:||.:....|..|:    :||      |::|...:..|...|..|||.|:      :.:
Zfish   179 LRDQTAQYMRSHADDFMPFLTNPNTGDMYTAEEFEKYCSDVADTAAWGGQLELKAL------SQV 237

  Fly   114 IYEPFDM----GRMVTYNKDY--KEILRIFMN---SMG-HFETVLTMQDV 153
            :..|.::    ...:|..::|  .:|..|:|.   .:| |:.:|..::|:
Zfish   238 LQLPIEVIQADSPCITIGEEYDKPKITLIYMRHAYGLGEHYNSVEPLKDL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	20/90 (22%)
otud6b	NP_956519.1	TMPIT	1..>67	CDD:285135
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		COG5539	2..282	CDD:227826	38/173 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	57..114
		Cys-loop. /evidence=ECO:0000250	152..158		1/5 (20%)
		OTU	154..278	CDD:280496	27/129 (21%)
		Variable-loop. /evidence=ECO:0000250	219..229		2/9 (22%)
		His-loop. /evidence=ECO:0000250	267..277		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578477
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840