DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and Otud4

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001178629.1	Gene:	Otud4 / 307774	RGDID:	1305606	Length:	1105	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	124/441 - (28%)
Similarity:	196/441 - (44%)	Gaps:	79/441 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFD 83
            |:|.:|.:..|:||.:..|.|.|||.|||||..:|..|.||||.|:||:....:.|..|:.|.|:
  Rat    24 PMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIRYLRDNREKFEAFIEGSFE 88

  Fly    84 EYLWHLGKTKTAGTILELGAMCHLYRRNVIIY-EPFDMGRMVTYNKDYKEILRIFMNSMGHFETV 147
            |||..|...:.....:|:.|:..:||::.:|| ||......||.|...:::|..|.|. .|::.|
  Rat    89 EYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNFPEKVLLCFSNG-NHYDIV 152

  Fly   148 LTMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTFKMGTE-------YEFDS-RGRA 204
            ..:...|.:|||||:.:::||:.:|: .||.   :.|:..:|.::..|       .|.|| :.::
  Rat   153 YPITYRDSSAVCQSLLYELLYEKVFK-TDVS---KIMMGLETSEVADESNSEISDSEDDSCKSKS 213

  Fly   205 IRLLCRNGRSFKLDRPESTICLLENSQMCPFHNRRLAMGGQFADFSCMRILLEENNIPFSYLVAK 269
            ......||  ||....|:           |.::      |..||            :|.|..|.|
  Rat   214 TAATDVNG--FKSSGSEN-----------PKNH------GNSAD------------LPLSRKVLK 247

  Fly   270 SMDPCRYRNVELTSAIEAR--REAYEFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSIDKK 332
            |:.|..|||||....::::  ::..::.|..| ..::.|.:|.|:||.|.:  ||...|..:..:
  Rat   248 SLSPAVYRNVEYEIWLKSKQAQQKRDYSIAAG-LQYEGGERCHVRLDHNGK--LSNADIHGVHSE 309

  Fly   333 KSVCKVFIEEQGKLVDVPSDNLHPLPPDEFKAWDFARKRPQRLHNSQMGRQSVQGDQQGFVPDPM 397
            ..  .|..||.|| ...|. ||.|.||:   :|:....:..:..||.....| ..|.:|
  Rat   310 NG--PVLSEELGK-KQTPK-NLKPPPPE---SWNTVSGKKMKKPNSGQNFHS-DTDYRG------ 360

  Fly   398 PGTAPSMPPPPVADPRPVNVTAQQPPVFGPSRWMEPTRPLMPNPLMIHQTG 448
                          |:.:|...:.|... |.|...|...:..:.|..|.||
  Rat   361 --------------PKNLNKPIKAPSAL-PPRLQHPPAGVRQHALSSHSTG 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	31/78 (40%)
Otud4	NP_001178629.1	OTU	42..>121	CDD:303090	32/78 (41%)
Otud4	NP_001178629.1	T4BSS_DotH_IcmK	556..>642	CDD:289093
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338854
Domainoid	1	1.000	65	1.000	Domainoid score	I9797
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46056
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1801
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.840