DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3251 and OTUD6A

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_997203.1	Gene:	OTUD6A / 139562	HGNCID:	32312	Length:	288	Species:	Homo sapiens

Alignment Length:	171	Identity:	38/171 - (22%)
Similarity:	77/171 - (45%)	Gaps:	30/171 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SEVLQRLASTEVRKARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVR- 65
            :|:.:.||..: |:..:.:...|..|.|..|.:..|...::|.:.:|      |.:.|.:|.:|
Human   115 AEMSEHLAGFK-REEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQ------LVFSVSVEMLRC 172

  Fly    66 ----YM----------FTKWKTFRRFVSGDFDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYE 116
                ||          |:..:|...|...||..|..::.:|...|..|||.|:.|:.:..:.:.:
Human   173 RTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQ 237

  Fly   117 PFDMGRMVTYNKDY--KEILRIFMN---SMG-HFETVLTMQ 151
            . |...:: ..::|  |.|:.:::.   |:| |:.:|..::
Human   238 A-DSPTLI-IGEEYVKKPIILVYLRYAYSLGEHYNSVTPLE 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	22/93 (24%)
OTUD6A	NP_997203.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		COG5539	5..271	CDD:227826	37/164 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..110
		Cys-loop. /evidence=ECO:0000250	146..152		1/5 (20%)
		OTU	147..269	CDD:280496	28/129 (22%)
		Variable-loop. /evidence=ECO:0000250	210..220		2/9 (22%)
		His-loop. /evidence=ECO:0000250	258..268		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840