DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3251 and alg13

DIOPT Version :9

Sequence 1:	NP_608851.1	Gene:	CG3251 / 33671	FlyBaseID:	FBgn0031622	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_002938835.2	Gene:	alg13 / 100145625	XenbaseID:	XB-GENE-22172432	Length:	855	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	123/462 - (26%)
Similarity:	200/462 - (43%)	Gaps:	95/462 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDE 84
            :|.:|....|:||....|||.|||.|:||::..|:.|.|:|..||.||....:.|..:|.|.|::
Frog    19 MDDYLASLGLYRKLTAKDASCLFRAVSEQLFFCQIHHPEIRKICVSYMRQNQELFESYVEGPFEK 83

  Fly    85 YLWHLGKTKTAGTILELGAMCHLYRRNVIIYEPFDMGRMVTYNKD--YKEILRIFMNSMGHFETV 147
            ||..|...|.:...||:.|:..::.::.|:|:  ..|:..||..|  ::..:.:..:|.||:::|
Frog    84 YLERLEDPKESAGQLEITALSLIFNQDFILYK--SPGKQPTYATDNNWEGKIMLCCSSNGHYDSV 146

  Fly   148 LTMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTFKMGTEYEFDSRGRAIRLLCRNG 212
            .|......||:||:|.::.||:.:|.:.:.:|    :...|.|:.||:              :|.
Frog   147 FTKAFQANAAICQAVLYECLYRDVFGVDEREL----LAAVDLFRSGTK--------------KNR 193

  Fly   213 RSFKLDRPESTI-CLLENSQMCPFHNR----RLAMGGQFADFSC------MRILLEENNIPFSYL 266
            .|......::.. |..|.:......||    .:..|..|.|...      ::.....|.:||.|.
Frog   194 NSASTGSEDANFDCSPEQTSKQSSDNRVKDWEVKGGDNFLDDKSRQTTDDVKSTENPNKMPFPYK 258

  Fly   267 VAKSMDPCRYRNVELTSAIEARREAY--EFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSI 329
            |.|::||..|||||....:::|:|..  ::.::.|.: :.:|.||||:|:...|  ....:||.:
Frog   259 VLKALDPEIYRNVEFDVWLDSRKELQKTDYMVFAGRH-YCLGDKCQVRLEPGGR--YYNAHIQEV 320

  Fly   330 DKKKSVCKVFIEEQGKLVDVPSDNLH------PLPPDEFKAW----------------------D 366
            .:..:...|||||..:...||..||.      |||     ||                      |
Frog   321 GQDSNAVTVFIEELAEKHLVPLINLKPVTQVIPLP-----AWNSSTNRKGGNYQKMTVGYNGELD 380

  Fly   367 FARKRPQRLHNSQMGRQSVQGDQQGFVPDPMPGTAPSMPPP-----------PVADPRPVNVTAQ 420
            ...|..:||.....|::: ||:        ||......||.           |...||.:|..|
Frog   381 LDLKSRKRLFKKVRGKET-QGN--------MPSYDHFRPPQSPHRQGRSYGIPKGSPRYMNRHA- 435

  Fly   421 QPPVFGP 427
               :.||
Frog   436 ---IIGP 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3251	NP_608851.1	OTU	36..>115	CDD:303090	29/78 (37%)
alg13	XP_002938835.2	OTU	36..>116	CDD:388712	30/81 (37%)
alg13	XP_002938835.2	TUDOR	299..347	CDD:119391	18/49 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10406
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007272
OrthoInspector	1	1.000	-	-		mtm9555
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1801
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.010