DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3355 and prss60.1

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	258	Identity:	102/258 - (39%)
Similarity:	137/258 - (53%)	Gaps:	41/258 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 CG-TPNVNRIVGGQQVRSNKYPWTAQL---VKGRHYPRLFCGGSLINDRYVLTAAHCVH------ 122
            || .|..||||||.......:||...|   :.|.|    ||||||||..:|||||||:.
Zfish    25 CGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGH----FCGGSLINSEWVLTAAHCLPRITTSS 85

  Fly   123 -----GNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMR 182
                 |...|..:...:|:|:         |...||||:|:.....||:|||.|.|.|..:..:|
Zfish    86 LLVFLGKTTQQGVNTYEINRT---------VSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIR 141

  Fly   183 PVCLPEANHNF-DGKTAVVAGWGLIKEG------GVTSNYLQEVNVPVITNAQCRQTRYKDKIAE 240
            ||||...|..| :|.::.:.|||.|:.|      |:    |||..:||:.|.||........:..
Zfish   142 PVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGI----LQETMIPVVPNDQCNALLGSGSVTN 202

  Fly   241 VMLCAGLVQQGGKDACQGDSGGPLIVNEGR-YKLAGVVSFGYGCAQKNAPGVYARVSKFLDWI 302
            .|:||||: |||:|.||||||||::..:.. :..:|:.|:|||||...:||||.|||::..||
Zfish   203 NMICAGLL-QGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	96/248 (39%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	97/249 (39%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	96/248 (39%)
		Tryp_SPc	34..267	CDD:238113	97/249 (39%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587872
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3731
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.790