DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3355 and prss60.2

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	254	Identity:	99/254 - (38%)
Similarity:	138/254 - (54%)	Gaps:	33/254 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 CGTPNVN-RIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIR 131
            ||...:| |||||.......:||...|...| |...|||||||:..:|||||||:.|..:...:
Zfish    25 CGQAPLNSRIVGGVNAPEGSWPWQVSLQSPR-YGGHFCGGSLISSEWVLTAAHCLPGVSESSLV- 87

  Fly   132 LLQIDRSSRDPGI-----VRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANH 191
             :.:.|.::. |:     .|.|.:..||.:|:.|...||:|||:|.|.|.....:|||||...|.
Zfish    88 -VYLGRRTQQ-GVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNS 150

  Fly   192 NFD-GKTAVVAGWGLIKEG------GVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQ 249
            .:. |.::.:.|||.::.|      |:    |||..:||:.|.:|........:...|:||||.
Zfish   151 VYSAGTSSWITGWGDVQAGVNLPAPGI----LQETMIPVVANDRCNAQLGSGTVTNNMICAGLA- 210

  Fly   250 QGGKDACQGDSGGPLIVNEGRYKL------AGVVSFGYGCAQKNAPGVYARVSKFLDWI 302
            :||||.||||||||::.     :|      ||:.|:|||||..|:||||.|||::..||
Zfish   211 KGGKDTCQGDSGGPMVT-----RLCTVWIQAGITSWGYGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	94/244 (39%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	95/245 (39%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	94/244 (39%)
		Tryp_SPc	34..267	CDD:238113	95/245 (39%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587870
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3731
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.790