DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and ea

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	114/312 - (36%)
Similarity:	150/312 - (48%)	Gaps:	63/312 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EQSIKAVRPPKSRNQCTAKQNCF------CGTPNVNRIVGGQQVRSNKYPWTA-------QLVKG 96
            |.|.:...|||.    ....|..      ||....|||.||.:.:.:::||.|       |..||
  Fly    95 ESSSETTPPPKP----NVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKG 155

  Fly    97 RHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRL---------------LQID-RSSRD---P 142
            .|     ||||||:.|||:||:|||:|.......||               .::| |..:|   |
  Fly   156 HH-----CGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPP 215

  Fly   143 GIVRKVVQTTVHPNYDP--NRIVNDVALLKLESPVPLTGNMRPVCLP-EAN---HNFDGKTAVVA 201
            .:...|.:|..||:|.|  ...|||:|||:|...|..|..:||:||| :.|   ..|||.|..||
  Fly   216 HLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVA 280

  Fly   202 GWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDK---IAEVMLCAGLVQQGGKDACQGDSGGP 263
            |||..::.. .||...:..|......:| |..|..:   :.:..:|||  .:.|.|:|:||||||
  Fly   281 GWGKTEQLS-ASNLKLKAAVEGFRMDEC-QNVYSSQDILLEDTQMCAG--GKEGVDSCRGDSGGP 341

  Fly   264 LI------VNEGRYKLAGVVSFG-YGCAQKNAPGVYARVSKFLDWIRKNTAD 308
            ||      ||. .|.|||||||| ..|.....||||..|.|::||| :||.:
  Fly   342 LIGLDTNKVNT-YYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI-QNTIE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	101/268 (38%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	102/270 (38%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	101/268 (38%)
		Tryp_SPc	128..389	CDD:238113	102/271 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940