DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and CG4613

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	258	Identity:	157/258 - (60%)
Similarity:	195/258 - (75%)	Gaps:	10/258 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NQCTAKQNCFCGTPNVNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVH 122
            |:|.   :|.||.|||||||||.|||:|||||.||:::|..   |||||:|||||||||||||||
  Fly   122 NRCA---SCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTF---LFCGGTLINDRYVLTAAHCVH 180

  Fly   123 G-NRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCL 186
            | :...:::||||:||||...|:.|.|.....|..|||..:|:|:|||:|:.|:||...|||.||
  Fly   181 GMDMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACL 245

  Fly   187 PEAN--HNFDGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQ 249
            | :|  .|||.:.|:||||||.:|||.||:.||||.||:|||||||.|.|:..|.:.|:|||.|:
  Fly   246 P-SNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVK 309

  Fly   250 QGGKDACQGDSGGPLIVNEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYC 312
            .||:|||||||||||||.:..::||||||||||||:.:|||||.|||::|:||..||.|.|||
  Fly   310 TGGRDACQGDSGGPLIVRDRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTRDSCYC 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	140/229 (61%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	141/231 (61%)
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	140/229 (61%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	139/228 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471759
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	1	0.900	-	-		E33208_3BJ04
Homologene	1	1.000	-	-		H56985
Inparanoid	1	1.050	153	1.000	Inparanoid score	I2933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D19085at50557
OrthoFinder	1	1.000	-	-		FOG0001240
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	11	10.900