DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and SPH93

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	89/255 - (34%)
Similarity:	131/255 - (51%)	Gaps:	25/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 CGTPNVN--RIVGG---QQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQ 127
            ||..|.|  ::|.|   .|.|..:|||...:.   |..:...|||||....|||.||.|.....:
  Fly   233 CGMSNANGLQMVEGITIDQARPAQYPWAVAIF---HNGQYLAGGSLIQPNVVLTVAHRVITIETE 294

  Fly   128 ITIRLLQID-RSSRDPGI--VRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEA 189
            :.:|....| :|.|:..:  .|:|.:..:|..:|.....|::|||.|.||..|..::|.:|||..
  Fly   295 LVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTP 359

  Fly   190 NHNFDGKTAVVAGWGLIK-EGGVTSNYLQEVNVPVITNAQC----RQTRY--KDKIAEVMLCAGL 247
            |.:|.|:...|||||.:: |....|..|::|.:.|:....|    |.||.  |.::.:.::|||
  Fly   360 NKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAG- 423

  Fly   248 VQQGGKDACQGDSGGPLIV-----NEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWI 302
             .:.|:|.|.||.|..|..     |.|.|:.||:|::|.||.|:..|.:|..||||.:||
  Fly   424 -GELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	83/244 (34%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	85/245 (35%)
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	83/238 (35%)
		Tryp_SPc	252..482	CDD:214473	80/234 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940