DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	304	Identity:	108/304 - (35%)
Similarity:	163/304 - (53%)	Gaps:	24/304 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QYQAPHQ---TLAQQFADVVDVVDPAEQSI--KAVRPPKSRNQCTAKQ----NCFCGT----PNV 73
            ::|.|.:   ||.:|..:::.....:.|||  :....|..|....|:.    |..||:    |.:
Mouse   119 KFQIPRKNAGTLKRQADNILQEKLQSSQSILKRDASLPYLREMNAAQAEHILNSDCGSGMEYPPI 183

  Fly    74 NRIVGGQQVRSNKYPWTAQL-VKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRLLQIDR 137
            .||..|:......:||.:.| |:|.|    .||.|||..::::|:||| ..|.....:..:...|
Mouse   184 ARIADGKPADKASWPWQSSLQVEGIH----LCGASLIGSQWLVTSAHC-FDNYKNPKLWTVSFGR 243

  Fly   138 SSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNFDGKTAV-VA 201
            :...|...|||....||.||..::..:|:|::||.|||..:.|:..||||:|......|:.| |.
Mouse   244 TLSSPLTTRKVESIIVHENYASHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKVFVT 308

  Fly   202 GWGLIKEGGVTSNYLQEVNVPVITNAQCRQTR-YKDKIAEVMLCAGLVQQGGKDACQGDSGGPLI 265
            |||.:|..|...|.||||.:.:|:|..|.|.. |...|:..|:|||.: .|..|||:|||||||:
Mouse   309 GWGALKANGPFPNSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFL-TGKLDACEGDSGGPLV 372

  Fly   266 VNEGRYK--LAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTA 307
            :::.|.|  |.|:||:|..|.::|.||:|.||:.:.|||:..|:
Mouse   373 ISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRDWIKSKTS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	90/231 (39%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	91/233 (39%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699	5/22 (23%)
		Tryp_SPc	185..411	CDD:214473	90/231 (39%)
		Tryp_SPc	186..414	CDD:238113	91/233 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920